ANTI-LC3 (APG8A) antibody produced in rabbit
SIGMA/SAB1305638 - IgG fraction of antiserum, buffered aqueous solution
Synonym: Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; MAP1 light chain 3-like protein 1; MAP1LC3A; Microtubule-
Product Type: Chemical
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| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 14272 Da |
| NCBI accession no. | NP_115903.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: 1:200 |
| western blot: 1:1000 | |
| UniProt accession no. | Q9H492 |
| Biochem/physiol Actions: | The gene MAP1LC3A (microtubule associated protein 1 light chain 3 α) or LC3 or autophagy-related protein 8A (APG8A) encodes a protein that serves as a marker of autophagosomes. It is found to be expressed on surviving oligodendrocytes in Nasu-Hakola disease brains and may be involved in the induction of oligodendrogliopathy. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | The gene autophagy-related protein 8A (APG8A), also referred to as MAP1LC3A (microtubule associated protein 1 light chain 3 α), is a homologue of Apg8p necessary for autophagy in yeast. The cytosolic form of the protein, upon processing, gets localized to the autophagosome membranes. The LC3 gene is mapped to human chromosome 20q11.22. |
| Physical form: | Supplied in PBS with 0.09% (W/V) sodium azide |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |