Saquinavir mesylate

SIGMA/S8451 - ≥98% (HPLC), powder

Synonym: (2S)-N1[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide methanesulfonate; Ro-31-8959

CAS Number: 149845-06-7
Empirical Formula (Hill Notation): C₃₈H₅₀N₆O₅·CH₄O₃S
Molecular Weight: 766.95
MDL Number: MFCD00944907
Linear Formula: C₃₈H₅₀N₆O₅·CH₄O₃S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-S8451-10MG	10 mg	$105.00 1/EA	Add To Favorites
45-S8451-50MG	50 mg	$428.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to tan
form	powder
InChI	1S/C38H50N6O5.CH4O3S/c1-38(2,3)43-37(49)32-20-26-14-7-8-15-27(26)22-44(32)23-33(45)30(19-24-11-5-4-6-12-24)41-36(48)31(21-34(39)46)42-35(47)29-18-17-25-13-9-10-16-28(25)40-29;1-5(2,3)4/h4-6,9-13,16-18,26-27,30-33,45H,7-8,14-15,19-23H2,1-3H3,(H2,39,46)(H,41,48)(H,42,47)(H,43,49);1H3,(H,2,3,4)/t26-,27+,30-,31-,32-,33+;/m0./s1
InChI key	IRHXGOXEBNJUSN-YOXDLBRISA-N
originator	Roche
Quality Level	100
SMILES string	CS(O)(=O)=O.CC(C)(C)NC(=O)[C@@H]1C[C@@H]2CCCC[C@@H]2CN1C[C@@H](O)[C@H](Cc3ccccc3)NC(=O)[C@H](CC(N)=O)NC(=O)c4ccc5ccccc5n4
solubility	DMSO: ≥5 mg/mL
storage condition	desiccated
storage temp.	2-8°C

Application:	Saquinavir mesylate may be used in cell signaling and immunology studies.
Biochem/physiol Actions:	Saquinavir is an HIV Protease Inhibitor used in antiretroviral therapy.
Biochem/physiol Actions:	Saquinavir is an HIV Protease Inhibitor used in antiretroviral therapy. It inhibits both HIV-1 and HIV-2 proteases. Studies have also looked at saquinavir as a possible anti-cancer agent.
Features and Benefits:	This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits:	This compound was developed by Roche . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description:	Saquinavir is a peptidomimetic hydroxyethylamine inhibitor, which is used to treat human immunodeficiency virus (HIV) infection.
Packaging:	10, 50 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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