Salbutamol
SIGMA/S8260
Synonym: α-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-α,α′-diol; Albuterol
CAS Number: 18559-94-9
Empirical Formula (Hill Notation): C13H21NO3
Molecular Weight: 239.31
EC Number: 242-424-0
MDL Number: MFCD00148978
Linear Formula: C13H21NO3
Product Type: Chemical
| InChI | 1S/C13H21NO3/c1-13(2,3)14 |
| InChI key | NDAUXUAQIAJITI-UHFFFAOYSA |
| originator | GlaxoSmithKline |
| Quality Level | 100 ![]() |
| SMILES string | CC(C)(C)NCC(O)c1ccc(O)c(C |
| solubility | methanol: complete 50 mg/ml, clear, colorless to yellow |
| Application: | Salbutamol was administered to primate model to study the bronchoconstriction in chronic allergic asthma.20 Salbutamol was used as a standard for rapid pharmacokinetic screening of human plasma samples using HPLC.21 |
| Biochem/physiol Actions: | β2-adrenoceptor agonist |
| Biochem/physiol Actions: | Salbutamol is a β2 adrenoceptor agonist with short acting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles and inhibits bronchoconstriction induced by adenosine-5′ -monophosphate (AMP).1 Salbutamol is particularly effective in treatment of asthma as it provides immediate relief.2 |
| Features and Benefits: | This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by GlaxoSmithKline . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Packaging: | 100, 250 mg in poly bottle |
| Packaging: | 25, 50 mg in glass insert |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H302 - H317 - H319 - H412 |
| Precautionary statements | P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| UNSPSC | 12352200 |


