Advanced Search



Swainsonine

SIGMA/S8195 - from Metarrhizium anisopliae, ≥98% (TLC)

Synonym: (1S,2R,8R,8aR)-1,2,8-Octahydroindolizidinetriol

CAS Number: 72741-87-8
Empirical Formula (Hill Notation): C8H15NO3
Molecular Weight: 173.21
MDL Number: MFCD00017554
Linear Formula: C8H15NO3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S8195-1MG 1 mg
 $633.00
1/EA		 Add To Favorites

 

antibiotic activity spectrum neoplastics
assay ≥98% (TLC)
biological source Metarrhizium anisopliae
color white to faint yellow
form lyophilized powder
InChI 1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7?,8-/m1/s1
InChI key FXUAIOOAOAVCGD-DCDLSZRSSA-N
mode of action enzyme | inhibits
Quality Level 200 
SMILES string O[C@@H]1CCCN2C[C@@H](O)[C@@H](O)C12
solubility H2O: soluble 1 mg/mL
storage condition (Keep container tightly closed in a dry and well-ventilated place.)
storage temp. 2-8°C
Application: Swainsonine is a potent inhibitor of various α-mannosidases, especially of α-mannosidase II. It inhibits glycoprotein processing and also acts as immune modulator.
Application: Swainsonine is an indolizidine alkaloid from the plant Metarrhizium anisopliae that is used as a potent α-mannosidase inhibitor. Product S8195 has been used in chemical inhibition assays of CHO Lec2 cells to inhibit glycosylation .
Biochem/physiol Actions: Swainsonine is a potent α-mannosidase inhibitor. It also has antimetastatic, antiproliferative, and immunomodulatory activity . It also inhibits glycoprotein processing.
Other Notes: Keep container tightly closed in a dry and well-ventilated place.
Packaging: 1MG
Preparation Note: Soluble in water, methanol, DMSO
Hazard Codes Xn
Risk Statements 20/21/22
Safety Statements 36
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Purity ≥98% (TLC)
Storage Temp. 2-8°C
UNSPSC 51102829

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Tariffs & Effects on Pricing

Tariff note: As we navigate the current environment of tariff surcharges and mid-year manufacturer price increases, we want to keep you informed. While we have avoided making specific decisions thus far, we anticipate that we will be forced to implement a cost adjustment policy to offset the fees we have already been absorbing. We are committed to transparency and moderation in this process.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top