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Salvinorin A

SIGMA/S8071 - ≥98% (HPLC), solid

Synonym: (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(3-furanyl)dodechydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester

CAS Number: 83729-01-5
Empirical Formula (Hill Notation): C23H28O8
Molecular Weight: 432.46
MDL Number: MFCD05664742
Linear Formula: C23H28O8
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S8071-1MG 1 mg
 $216.00
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assay ≥98% (HPLC)
color white
drug control regulated under CDSA - not available from Sigma-Aldrich Canada; Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet
form solid
InChI 1S/C23H28O8/c1-12(24)30-16-9-15(20(26)28-4)22(2)7-5-14-21(27)31-17(13-6-8-29-11-13)10-23(14,3)19(22)18(16)25/h6,8,11,14-17,19H,5,7,9-10H2,1-4H3/t14-,15-,16-,17-,19-,22-,23-/m0/s1
InChI key OBSYBRPAKCASQB-AGQYDFLVSA-N
Quality Level 100 
SMILES string [H][C@@]12CC[C@@]3(C)[C@@H](C[C@H](OC(C)=O)C(=O)[C@]3([H])[C@@]1(C)C[C@H](OC2=O)c4ccoc4)C(=O)OC
solubility DMSO: ≥10 mg/mL
  ethanol: ~3 mg/mL
storage condition protect from light
storage temp. −20°C
Application: Salvinorin A was administered to rats to study effects on lactic acid-stimulated stretching.1
Biochem/physiol Actions: Salvanorin A is a non-nitrogenous κ opioid receptor agonist.
Biochem/physiol Actions: Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A displays high affinity at both native (Ki=4.3 nm) and cloned (Ki=16 nm) κ -opioid receptors. Preliminary studies suggest that Salvanorin A is chemically unique among the psychtropic drugs and does not bind to any known receptor.
Features and Benefits: This compound is featured on the Opioid Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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