(±)-Sulpiride
SIGMA/S8010
Synonym: (±)
CAS Number: 15676-16-1
Empirical Formula (Hill Notation): C15H23N3O4S
Molecular Weight: 341.43
EC Number: 239-753-7
MDL Number: MFCD00055061
Linear Formula: C15H23N3O4S
Product Type: Chemical
| color | white |
| form | powder |
| InChI | 1S/C15H23N3O4S/c1-3-18-8- |
| InChI key | BGRJTUBHPOOWDU-UHFFFAOYSA |
| originator | Sanofi Aventis |
| Quality Level | 100 ![]() |
| SMILES string | CCN1CCCC1CNC(=O)c2cc(ccc2 |
| solubility | 0.1 M HCl: soluble |
| 45% (w/v) aq 2-hydroxypropyl-β-cyclode |
|
| ethanol: soluble | |
| H2O: slightly soluble | |
| storage temp. | 2-8°C |
| Application: | (±)-Sulpiride was used to study the effect of dopamine D2 receptor signaling on calcium channels in rat pituitary melanotropic cells.47 |
| Biochem/physiol Actions: | (±)-Sulpiride is a D2 dopamine antagonist and an effective treatment for schizophrenia when used in combination with clozapine, a relatively weak D2-dopaminergic antagonist. It is an antipsychotic agent and also exhibits neuroleptic properties but poorly penetrates the central nervous system.45,46 |
| Features and Benefits: | This compound was developed by Sanofi Aventis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Preparation Note: | Solutions may be stored for several days at 4 °C. |
| Symbol | GHS08 |
| Signal word | Warning |
| Hazard statements | H361 |
| Precautionary statements | P280 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |


