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(±)-Sulpiride

SIGMA/S8010

Synonym: (±)-5-(Aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide; (±)-N-1-(Ethylpyrrolidin-2-ylmethyl)-2-methoxy-5-sulfamoylbenzamide

CAS Number: 15676-16-1
Empirical Formula (Hill Notation): C15H23N3O4S
Molecular Weight: 341.43
EC Number: 239-753-7
MDL Number: MFCD00055061
Linear Formula: C15H23N3O4S
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-S8010-25G 25 g
$136.00
1/EA
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45-S8010-100G 100 g
$457.00
1/EA
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color white
form powder
InChI 1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)
InChI key BGRJTUBHPOOWDU-UHFFFAOYSA-N
originator Sanofi Aventis
Quality Level 100 
SMILES string CCN1CCCC1CNC(=O)c2cc(ccc2OC)S(N)(=O)=O
solubility 0.1 M HCl: soluble
  45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 8.0 mg/mL
  ethanol: soluble
  H2O: slightly soluble
storage temp. 2-8°C
Application: (±)-Sulpiride was used to study the effect of dopamine D2 receptor signaling on calcium channels in rat pituitary melanotropic cells.47
Biochem/physiol Actions: (±)-Sulpiride is a D2 dopamine antagonist and an effective treatment for schizophrenia when used in combination with clozapine, a relatively weak D2-dopaminergic antagonist. It is an antipsychotic agent and also exhibits neuroleptic properties but poorly penetrates the central nervous system.45,46
Features and Benefits: This compound was developed by Sanofi Aventis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Preparation Note: Solutions may be stored for several days at 4 °C.
Symbol GHS08  GHS08
Signal word Warning
Hazard statements H361
Precautionary statements P280
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 12352200

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