Ovalbumin (257-264) chicken

SIGMA/S7951 - ≥97% (HPLC)

Synonym: L-seryl-L-isoleucyl-L-isoleucyl-L-asparaginyl-L-phenylalanyl-L-a-glutamyl-L-lysyl- L-Leucine trifluoroacetate; OVA (257 - 264); SIINFEKL trifluoroacetate salt; Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu trifluoroaceate; pOV8

CAS Number: 138831-86-4 (free base)
Empirical Formula (Hill Notation): C₄₅H₇₄N₁₀O₁₃ · xC₂HF₃O₂
Molecular Weight: 963.13 (free base basis)
MDL Number: MFCD18452854
Linear Formula: C₄₅H₇₄N₁₀O₁₃ · xC₂HF₃O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-S7951-1MG	1 mg	$227.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥97% (HPLC)
color	white to off-white
form	lyophilized powder
InChI	1S/C45H74N10O13.C2HF3O2/c1-7-25(5)36(55-44(66)37(26(6)8-2)54-38(60)28(47)23-56)43(65)52-32(22-34(48)57)42(64)51-31(21-27-14-10-9-11-15-27)41(63)50-30(17-18-35(58)59)40(62)49-29(16-12-13-19-46)39(61)53-33(45(67)68)20-24(3)4;3-2(4,5)1(6)7/h9-11,14-15,24-26,28-33,36-37,56H,7-8,12-13,16-23,46-47H2,1-6H3,(H2,48,57)(H,49,62)(H,50,63)(H,51,64)(H,52,65)(H,53,61)(H,54,60)(H,55,66)(H,58,59)(H,67,68);(H,6,7)/t25-,26-,28-,29-,30-,31-,32-,33-,36-,37-;/m0./s1
InChI key	BRUCWCULSHVYBQ-VPZPQSBKSA-N
Quality Level	200
SMILES string	OC(=O)C(F)(F)F.CC[C@H](C)[C@H](NC(=O)[C@@H](N)CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(O)=O
solubility	H₂O: >1 mg/mL
storage temp.	−20°C

Amino Acid Sequence:	Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu
Application:	Ovalbumin (257-264) chicken has been used to trigger T cell activation in immunology studies.
Application:	Ovalbumin (257-264) chicken has been used: • to sensitize mice to generate an asthmatic model • in the stimulation of splenocytes • for treating dendritic cells to be used as a positive control in cross-presentation studies
Biochem/physiol Actions:	Ovalbumin (257-264) chicken is an antigenic peptide and triggers immune response. Administration of the ovalbumin peptide in pregnant mice helps in surpassing ear development anomalies.
Biochem/physiol Actions:	SIINFEKL is a class I (Kb)-restricted peptide epitope of ovalbumin (OVA); the ovalbumin fragment is presented by the class I MHC molecule, H-2Kb.
Other Notes:	Lyophilized from 0.1% TFA in H2O
Packaging:	1 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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