SMER3
SIGMA/S7826 - ≥98% (HPLC)
Synonym: 9H-
CAS Number: 67200-34-4
Empirical Formula (Hill Notation): C11H4N4O2
Molecular Weight: 224.18
MDL Number: MFCD00451458
Linear Formula: C11H4N4O2
Product Type: Chemical
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This image depicts S7826-25MG.
This image depicts S7826-25MG.
| assay | ≥98% (HPLC) |
| color | yellow |
| form | powder |
| InChI | 1S/C11H4N4O2/c16-9-6-4-2- |
| InChI key | SFSSAKVWCKFRHE-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | O=C1c2ccccc2-c3nc4nonc4nc |
| solubility | DMSO: ≥30 mg/mL |
| storage temp. | 2-8°C |
| Application: | SMER3 may be used in cell signaling studies. |
| Biochem/physiol Actions: | Inhibition of SCFMet30 by SMER3 blocks the ubiquitination of Met4 and activates the Met4-containing transcription complex. The induction of MET-genes results in cell cycle arrest and reduced cell proliferation.1 |
| Biochem/physiol Actions: | Small molecule enhancer of rapamycin (SMER); specific inhibitor of Ubiquitin E3 ligase. |
| Packaging: | 5, 25 mg in glass bottle |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |