Sodium selenite
SIGMA/S5261 - BioReagent, suitable for cell culture, ≥98%
Synonym: Selenious acid; Sodium salt
CAS Number: 10102-18-8
Empirical Formula (Hill Notation): Na2O3Se
Molecular Weight: 172.94
EC Number: 233-267-9
MDL Number: MFCD00003489
Linear Formula: Na2SeO3
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: S5261-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: S5261-10G
| assay | ≥98% |
| biological source | synthetic (inorganic) |
| form | powder |
| InChI | 1S/2Na.H2O3Se/c;;1-4(2)3/ |
| InChI key | BVTBRVFYZUCAKH-UHFFFAOYSA |
| mp | >350 °C (lit.) |
| product line | BioReagent |
| Quality Level | 200  |
| SMILES string | [Na+].[Na+].[O-][Se]([O-] |
| solubility | water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow |
| technique(s) | cell culture | mammalian: suitable |
| Application: | Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis. |
| Application: | This product is cell culture tested (0.005 mg/L) and is appropriate for use in cell culture applications. |
| Packaging: | 10, 25, 100 g in glass bottle |
| Symbol |   GHS06,GHS09 |
| Signal word | Danger |
| Hazard statements | H300 + H330 - H315 - H317 - H319 - H411 |
| Precautionary statements | P260 - P273 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | T+,N |
| Risk Statements | 23-28-31-43-51/53 |
| Safety Statements | 28-36/37-45-61 |
| RIDADR | UN2630 - class 6.1 - PG 1 - EHS - Selenites, HI: all (not BR) |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Supplemental Hazard Statements | EUH031 |
| Purity | ≥98% |
| mp | >350 °C (lit.) |
| UNSPSC | 12352205 |