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Sphingosylphosphorylcholine

SIGMA/S4257 - ≥98%, powder

Synonym: (2S,3R,4E)-2-Amino-4-octadecene-3-hydroxy-1-phosphocholine; 2-[[[(2-Amino-3-hydroxy-4-octadecenyl)oxy]hydroxy-phosphinyl]oxy]-N,N,N-trimethylethanaminium inner salt; D-erythro-Sphingosine phosphocholine; Lyso SM (d18:1); Lysosphingomyelin

CAS Number: 1670-26-4
Empirical Formula (Hill Notation): C23H49N2O5P
Molecular Weight: 464.62
MDL Number: MFCD02259287
Linear Formula: C23H49N2O5P
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S4257-10MG 10 mg
 $341.00
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45-S4257-25MG 25 mg
 $811.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: S4257-25MG

 

assay ≥98%
color light yellow
form powder
InChI 1S/C23H49N2O5P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)22(24)21-30-31(27,28)29-20-19-25(2,3)4/h17-18,22-23,26H,5-16,19-21,24H2,1-4H3/b18-17+/t22-,23+/m0/s1
InChI key JLVSPVFPBBFMBE-HXSWCURESA-N
Quality Level 200 
SMILES string [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(N)COP([O-])(OCC[N+](C)(C)C)=O
solubility chloroform/methanol (2:1): complete 10 mg/ml, clear to slightly hazy, colorless to light yellow
storage temp. −20°C
Application: Neurotrophic effects of Sphingosylphosphorylcholine were studied in cerebellar granule neurons of mice and PC-12 cells.
Biochem/physiol Actions: Sphingosylphosphorylcholine (SPC) is a bioactive lipid that mediates intracellular and extracellular signaling. It mobilizes Ca2+ from intracellular stores via an IP3-independent pathway. It stimulates the production of CCL2 that may contribute to development of atherosclerosis. SPC is a ligand for endothelial differentiation gene receptor 3 (EDG3).
Packaging: 10 mg in poly bottle
Packaging: 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98%
Storage Temp. −20°C
UNSPSC 12352211

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