Suberic acid bis(N-hydroxysuccinimide ester)
SIGMA/S1885 - ≥95%, powder
Synonym: Disuccinimidyl suberate; Disuccinimidyl octanedioate; Disuccinimidyl suberate (DSS)
CAS Number: 68528-80-3
Empirical Formula (Hill Notation): C16H20N2O8
Molecular Weight: 368.34
MDL Number: MFCD00049059
Linear Formula: C16H20N2O8
Product Type: Chemical
| assay | ≥95% |
| form | powder |
| functional group | imide |
| InChI | 1S/C16H20N2O8/c19-11-7-8- |
| InChI key | ZWIBGKZDAWNIFC-UHFFFAOYSA |
| Quality Level | 200 ![]() |
| reaction suitability | reagent type: cross-linking reagent |
| SMILES string | O=C(CCCCCCC(=O)ON1C(=O)CC |
| solubility | aqueous buffer: slightly soluble (may require 5-10% organic solvent in coupling mixture.) |
| chloroform: 50 mg/mL | |
| DMF: soluble | |
| storage temp. | 2-8°C |
| Application: | Suberic acid bis(N-hydroxysuccinimide ester) has been: • supplemented in pierce lysis buffer used for immunoprecipitation • used to conjugate the oligonucleotide standards to gelatin • used in cross-linking of ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain) oligomers |
| General description: | Suberic acid bis(N-hydroxysuccinimide ester) is a homobifunctional cross-linking reagent with amine reactivity. Typically coupled to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). Suberic acid bis(N-hydroxysuccinimide ester) incorporates an 8-atom linker. |
| Packaging: | 1, 5 g in poly bottle |
| Packaging: | 500 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352100 |

