Monoclonal Anti-SERCa2 ATPase antibody produced in mouse
SIGMA/S1314 - clone 2A7-A1, ascites fluid
Synonym: Anti-ATP2B; Anti-DAR; Anti-DD; Anti-SERCA2
MDL Number: MFCD00802883
Product Type: Chemical
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| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 2A7-A1, monoclonal |
| conjugate | unconjugated |
| contains | 0.05% sodium azide |
| mol wt | antigen 110 kDa |
| Quality Level | 200  |
| shipped in | dry ice |
| species reactivity | guinea pig, human, canine, mouse, rat, rabbit |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoprecipitation (IP): suitable |
| western blot: suitable | |
| UniProt accession no. | P16615  |
| Application: | Anti-SERCa2 ATPase antibody has been used in western blotting and immunocytochemistry. |
| Biochem/physiol Actions: | Mutation of SERCa2 ATPase (sarco/endoplasmic reticulum calcium-ATPase 2) or ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2) causes Dyskeratosis follicularis. SERCA2a plays a major role in controlling cardiomyocyte Ca2+. ATP2A2 mutation may cause Darier disease (DD). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | SERCa2 ATPase (sarco/endoplasmic reticulum calcium-ATPase 2) is also known as ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2). It codes for SERCA2a and SERCA2b, that are expressed in all tissues. SERCA2a is highly expressed in heart. SERCa2 is located on human chromosome 12q24.1. |
| Immunogen: | canine cardiac sarcoplasmic reticulum vesicles |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |