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Succinyl coenzyme A sodium salt

SIGMA/S1129 - ≥85%

Synonym: Succinyl CoA sodium salt

CAS Number: 108347-97-3
Empirical Formula (Hill Notation): C25H40N7O19P3S
Molecular Weight: 867.61
Linear Formula: C25H40N7O19P3S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S1129-5MG 5 mg
 $266.00
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45-S1129-25MG 25 mg
 $1000.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: S1129-25MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: S1129-5MG

 

assay ≥85%
form powder
InChI 1S/C25H40N7O19P3S/c1-25(2,20(38)23(39)28-6-5-14(33)27-7-8-55-16(36)4-3-15(34)35)10-48-54(45,46)51-53(43,44)47-9-13-19(50-52(40,41)42)18(37)24(49-13)32-12-31-17-21(26)29-11-30-22(17)32/h11-13,18-20,24,37-38H,3-10H2,1-2H3,(H,27,33)(H,28,39)(H,34,35)(H,43,44)(H,45,46)(H2,26,29,30)(H2,40,41,42)/p-2/t13-,18-,19-,20?,24-/m1/s1
InChI key VNOYUJKHFWYWIR-FZEDXVDRSA-L
Quality Level 200 
SMILES string [Na+].[Na+].CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)([O-])=O)n2cnc3c(N)ncnc23)C(O)C(=O)NCCC(=O)NCCSC(=O)CCC([O-])=O
solubility water: 50 mg/mL, clear, colorless
storage temp. −20°C
Application: Succinyl coenzyme A sodium salt has been used:
• for the nonenzymatic succinylation of lysine in vitro,
• as a substrate for adipic acid biosynthesis in recombinant E. coli
• in isocitrate dehydrogenase (ICDH) treatment for the succinylation of proteins
• as a substrate to study the specificity and kinetics of enzymes such as acetate:succinate CoA-transferase and 5-aminolevulinate synthase (ALA synthase)
Biochem/physiol Actions: Succinyl CoA is an intermediate in the citric acid cycle. It is formed by α-ketoglutarate dehydrogenase by the decarboxylation of α-ketoglutarate. Succinyl CoA is also formed from propionyl CoA during the β-oxidation of odd-chain fatty acids. Succinyl CoA serves as a precursor in heme synthesis. It is also required for the oxidation of ketone bodies.
Packaging: 25 mg in poly bottle
Packaging: 5 mg in glass bottle
Purity ≥85%
Storage Temp. −20°C
UNSPSC 41106305

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