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D-Saccharic acid 1,4-lactone monohydrate

SIGMA/S0375 - ≥98.0% (HPLC)

Synonym: D-Glucaric acid-1,4-lactone; D-Saccharolactone

CAS Number: 61278-30-6
Empirical Formula (Hill Notation): C6H8O7 · H2O
Molecular Weight: 210.14
MDL Number: MFCD00149334
Linear Formula: C6H8O7 · H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S0375-250MG 250 mg
 $0.00
1/EA
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45-S0375-1G 1 g
 $246.00
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45-S0375-5G 5 g
 $1060.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: S0375-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: S0375-250MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: S0375-5G

 

assay ≥98.0% (HPLC)
color white
form powder
impurities ≤10.0% water (Karl Fischer)
InChI 1S/C6H8O7.H2O/c7-1-2(8)6(12)13-4(1)3(9)5(10)11;/h1-4,7-9H,(H,10,11);1H2/t1-,2-,3+,4+;/m1./s1
InChI key NPFKVZHSFSFLPU-QGBSHYGGSA-N
mp 91 - 93 °C ((196 - 199 °F ))
Quality Level 200 
SMILES string O.O[C@@H]1[C@@H](O)C(=O)O[C@@H]1[C@H](O)C(O)=O
solubility water: 50 mg/mL, clear, colorless to faintly yellow
storage temp. 2-8°C
Application: D-Saccharic acid 1,4-lactone monohydrate has been used as a constituent of phosphate buffer to block incidental β-glucuronidase activity in Streptococcus pneumoniae hyaluronan lyase (SpnHL) activity assay. It has also been used as a component of reaction mixture in Iduronidase activity assay and UDP-glucuronosyltransferase 1 (UGT1A1) inhibition assay.
General description: D-Saccharic acid 1,4-lactone monohydrate (DSAL) has an ability to inhibit the activity of β-glucuronidase enzyme.It also potentially inhibits Klotho deglycosylation of excitatory amino acid transporters (EAATs) and peptide transporters (PEPTs).
Other Notes: To gain a comprehensive understanding of our extensive range of Monosaccharides  for your research, we encourage you to visit our Carbohydrates  Category page.
Packaging: 1, 5 g in poly bottle
Packaging: 250 mg in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98.0% (HPLC)
mp 91 - 93 °C ((196 - 199 °F ))
Storage Temp. 2-8°C
UNSPSC 12352201

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