BIS-TRIS

SIGMA/RES1161B-A7

Synonym: 2,2-Bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol; 2-Bis(2-hydroxyethyl)amino-2-(hydroxymethyl)-1,3-propanediol; Bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane

CAS Number: 6976-37-0
Empirical Formula (Hill Notation): C₈H₁₉NO₅
Molecular Weight: 209.24
EC Number: 230-237-7
MDL Number: MFCD00002853
Linear Formula: C₈H₁₉NO₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-RES1161B-A701X	100 g	$0.00 1/EA CALL FOR PRICE	Add To Favorites
45-RES1161B-A705X	25 kg	$0.00 1/EA CALL FOR PRICE	Add To Favorites

Photo is meant to be representative of product you will receive if ordered. Additional information is printed on actual labels and package types are subject to change.

Properties
Descriptions
Safety Info.
Basic Data

biological source	synthetic
foreign activity	Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
form	powder
impurities	Endotoxin, microbial, and trace metals, tested
InChI	1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2
InChI key	OWMVSZAMULFTJU-UHFFFAOYSA-N
pKa (25 °C)	6.5
Quality Level	400
SMILES string	OCCN(CCO)C(CO)(CO)CO
solubility	H₂O: 0.1 M, clear, colorless (aqueous)
suitability	suitable for manufacturing use
technique(s)	cell culture \| mammalian: suitable
useful pH range	5.8-7.2

Application:	Bis Tris is a commonly used biological buffer for very broad usage in biological systems such as diagnostics, electrophoresis and protein based bioprocessing. The pKa of Bis Tris is 6.36 which makes it a good candidate for biological based formulations. Bis Tris is used in a wide variety of biological applications including culture media, electrophoresis separations and diagnostic reagent formulations.
General description:	Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program. M-Clarity Program Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step. Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
Legal Information:	SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
Packaging:	Product is available in the following package sizes: RES1161B-A701X: 100g container RES1161B-A702X 1kg container RES1161B-A704X: 10kg container RES1161B-A705X: 25kg container

Symbol	GHS05
Signal word	Danger
Hazard statements	H318
Precautionary statements	P280 - P305 + P351 + P338 + P310
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

UNSPSC

12161705

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