MES monohydrate
SIGMA/RES0113M-A7
Synonym: 2-
CAS Number: 145224-94-8
Empirical Formula (Hill Notation): C6H13NO4S · H2O
Molecular Weight: 213.25
EC Number: 224-632-3
MDL Number: MFCD00149409
Linear Formula: C6H13NO4S · H2O
Product Type: Chemical
Photo is meant to be representative of product you will receive if ordered. Additional information is printed on actual labels and package types are subject to change.
| biological source | synthetic |
| foreign activity | Cytotoxicity, DNase, NICKase, RNase, and Protease; tested |
| form | powder |
| impurities | Endotoxin, microbial, and trace metals, tested |
| InChI | 1S/C6H13NO4S.H2O/c8-12(9, |
| InChI key | MIIIXQJBDGSIKL-UHFFFAOYSA |
| mp | >300 °C (lit.) |
| pKa (25 °C) | 6.1 |
| Quality Level | 400  |
| SMILES string | O.OS(=O)(=O)CCN1CCOCC1 |
| suitability | suitable for manufacturing use |
| technique(s) | cell culture | mammalian: suitable |
| useful pH range | 5.5-6.7 |
| Application: | MES is a biological buffer often referred to as a “Good’s” buffer .The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES is considered to be non-toxic to culture cell lines, highly water soluble and provides high solution clarity. MES is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream), and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors. |
| General description: | Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program. M-Clarity Program Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step. Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs. |
| Legal Information: | SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Packaging: | Product is available in the following package sizes: RES0113M-A701X: 100g container RES0113M-A703X: 5kg container RES0113M-A705X: 25kg container RES0113M-A706X: 50kg container |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | >300 °C (lit.) |
| UNSPSC | 12161700 |