Rosmarinic acid
SIGMA/R4033 - ≥98% (HPLC), from Rosemarinus officinalis L.
Synonym: (R)-O-
CAS Number: 20283-92-5
Empirical Formula (Hill Notation): C18H16O8
Molecular Weight: 360.31
MDL Number: MFCD00017740
Linear Formula: C18H16O8
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: R4033-10MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: R4033-50MG
| application(s) | metabolomics vitamins, nutraceuticals, and natural products |
| assay | ≥98% (HPLC) |
| biological source | Rosemarinus officinalis L. |
| color | white to faint beige |
| form | powder |
| InChI | 1S/C18H16O8/c19-12-4-1-10 |
| InChI key | DOUMFZQKYFQNTF-WUTVXBCWSA |
| mp | 171-175 °C (lit.) |
| Quality Level | 100  |
| SMILES string | OC(=O)[C@@H](Cc1ccc(O)c(O |
| solubility | H2O: 1 mg/mL, clear, colorless |
| storage condition | protect from light |
| storage temp. | 2-8°C |
| Application: | Rosmarinic acid has been used: • to see its protective effects on the human endothelial cell line (EA.hy926) to treat diabetic atherosclerosis • to test its effect in 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) induced Parkinson′s disease (PD) models on attenuating inflammatory responses and microglia activation • to test its neuroprotective effects on dopaminergic neurons • to test its effects on sperm motility, viability and on intracellular calcium ion concentration • as a reference standard in capillary zone electrophoresis (CZE) method |
| Biochem/physiol Actions: | Rosmarinic acid (RosA) is a well-appreciated agent used in several diabetic conditions and complications such as diabetic nephropathy, diabetic neuropathy and diabetic atherosclerosis. It has also been implicated to be a neuroprotective agent for several neurological disorders such as Alzheimer′s disease, Parkinson′s disease, and epilepsy by suppressing their conditions. |
| General description: | Rosmarinic acid is a naturally occurring polyphenolic compound found in plants of the Boraginaceae family and Nepetoideae subfamily. It is an ester of caffeic acid as well as 3,4-dihydroxy-phenyllacti |
| Packaging: | 10, 50 mg in glass bottle |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| mp | 171-175 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352106 |