Rifampicin
SIGMA/R3501 - ≥95% (HPLC), powder or crystals
Synonym: 3-
CAS Number: 13292-46-1
Empirical Formula (Hill Notation): C43H58N4O12
Molecular Weight: 822.94
EC Number: 236-312-0
MDL Number: MFCD00151389
Linear Formula: C43H58N4O12
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: R3501-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: R3501-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: R3501-5G
| antibiotic activity spectrum | Gram-negative bacteria |
| Gram-positive bacteria | |
| mycobacteria | |
| viruses | |
| assay | ≥95% (HPLC) |
| color | Reddish-brown |
| form | powder or crystals |
| InChI | 1S/C43H58N4O12/c1-21-12-1 |
| InChI key | JQXXHWHPUNPDRT-WLSIYKJHSA |
| mode of action | protein synthesis | interferes |
| pI | 4.84 |
| pKa | 1.7 (4-hydroxyl group) |
| 7.9 (4-piperazine nitrogen) | |
| Quality Level | 200  |
| SMILES string | CO[C@H]1C=CO[C@@]2(C)Oc |
| storage temp. | −20°C |
| Application: | Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. It is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, primary biliary cirrhosis (PBC). It has been shown to cause hepatitis. |
| Biochem/physiol Actions: | Inhibits the assembly of DNA and protein into mature virus particles. |
| Biochem/physiol Actions: | Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase. |
| Biochem/physiol Actions: | Rifampicin inhibits the assembly of DNA and protein into mature virus particles. It inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase, which results in cell death. |
| General description: | Chemical structure: macrolide |
| Other Notes: | Keep container tightly closed in a dry and well-ventilated place.Product is sensitive to light and moisture.Store under inert gas. Keep in a dry place |
| Packaging: | 1, 5, 25 g in glass bottle |
| Packaging: | 250 mg in glass insert |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 - H315 - H319 - H335 - H362 |
| Precautionary statements | P260 - P263 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 51283601 |