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RS-127445 hydrochloride

SIGMA/R2533 - ≥98% (HPLC), powder

Synonym: 2-Amino-4-(4-fluoronaphth-1-yl)-6-isopropylpyrimidine hydrochloride

CAS Number: 199864-86-3
Empirical Formula (Hill Notation): C17H16FN3 · HCl
Molecular Weight: 317.79
MDL Number: MFCD11112196
Linear Formula: C17H16FN3 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-R2533-5MG 5 mg
 $133.00
1/EA		 Add To Favorites
45-R2533-25MG 25 mg
 $514.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to tan
form powder
InChI 1S/C17H16FN3.ClH/c1-10(2)15-9-16(21-17(19)20-15)13-7-8-14(18)12-6-4-3-5-11(12)13;/h3-10H,1-2H3,(H2,19,20,21);1H
InChI key MKJPYBJBPRFMHL-UHFFFAOYSA-N
originator Roche
Quality Level 100 
SMILES string Cl.CC(C)c1cc(nc(N)n1)-c2ccc(F)c3ccccc23
solubility DMSO: ≥20 mg/mL
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: RS-127445 is a selective; high affinity; orally bioavailable serotonin 5-HT2B receptor antagonist.
Biochem/physiol Actions: RS-127445 is a selective; high affinity; orally bioavailable serotonin 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi=9.5) and 1,000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites.
Features and Benefits: This compound was developed by Roche . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 5, 25 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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