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all trans-Retinal

SIGMA/R2500 - powder, ≥98%

Synonym: Vitamin A aldehyde

CAS Number: 116-31-4
Empirical Formula (Hill Notation): C20H28O
Molecular Weight: 284.44
MDL Number: MFCD00001550
Linear Formula: C20H28O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-R2500-25MG 25 mg
 $73.20
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45-R2500-100MG 100 mg
 $100.00
1/EA		 Add To Favorites
45-R2500-500MG 500 mg
 $237.00
1/EA		 Add To Favorites
45-R2500-1G 1 g
 $408.00
1/EA		 Add To Favorites
Representative of vacuum-sealed clear ampule packaging. Non-uniform tips are an inherent feature in this sealing process.

 

assay ≥98%
biological source synthetic (organic)
color yellow
form powder
InChI 1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
InChI key NCYCYZXNIZJOKI-OVSJKPMPSA-N
mp 62-64 °C
Quality Level 200 
shipped in dry ice
SMILES string [H]C(=O)C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C
storage temp. −20°C
technique(s) HPLC: suitable
Application: All trans-Retinal has been used:
• in optogenetic experiments
• in electrophysiological experiment
• to study the effect of AKR1B10 (aldo-keto reductase (AKR) superfamily member) on the conversion of retinal to retinol in the airway epithelium
• in decidual transformation of human endometrial stromal cells
Biochem/physiol Actions: All-trans retinal is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Retinoic acid is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells. Retinal isomers are also chromophores that bind to opsins, a family of G-protein-linked transmembrane proteins, to form photosensitive receptors in visual and nonvisual systems. All-trans retinal is a potent photosensitizer.
General description: All trans-Retinal is one of the major derivatives of vitamin A group. A variety of food serves as a source of vitamin A. It is predominant in liver and among the brightly colored vegetables.
Packaging: 1 g in ampule
Packaging: 25, 100, 500 mg in ampule
Packaging: Sealed ampule.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98%
mp 62-64 °C
Storage Temp. −20°C
UNSPSC 12352205

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