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PF-05190457

SIGMA/PZ0270 - ≥95% (HPLC)

Synonym: 1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-ethanone; 2-(2-Methylimidazo[2,1-b][1,3]thiazol-6-yl)-1-{2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-ylethanone; PF 5190457; PF-5190457

CAS Number: 1334782-79-4
Empirical Formula (Hill Notation): C29H32N6OS
Molecular Weight: 512.67
MDL Number: MFCD28411390
Linear Formula: C29H32N6OS
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-PZ0270-5MG 5 mg
 $129.00
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45-PZ0270-25MG 25 mg
 $509.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts PZ0270-5MG.

 

assay ≥95% (HPLC)
color white to beige
form powder
InChI 1S/C29H32N6OS/c1-19-11-25(31-18-30-19)22-3-5-24-21(12-22)4-6-26(24)35-16-29(17-35)7-9-33(10-8-29)27(36)13-23-15-34-14-20(2)37-28(34)32-23/h3,5,11-12,14-15,18,26H,4,6-10,13,16-17H2,1-2H3/t26-/m1/s1
InChI key ZIUDADZJCKGWKR-AREMUKBSSA-N
optical activity [α]/D +40 to +60°, c = 0.5 in methanol
Quality Level 100 
SMILES string CC1=CN2C(S1)=NC(CC(N3CCC4(CN([C@H](CCC5=C6)C5=CC=C6C7=NC=NC(C)=C7)C4)CC3)=O)=C2
solubility DMSO: 2 mg/mL, clear
storage temp. room temp
Biochem/physiol Actions: PF-05190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-05190457 potently increases insulin secretion in glucose-stimulated human islets.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. room temp
UNSPSC 51111800

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