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PF-06273340

SIGMA/PZ0254 - ≥98% (HPLC)

Synonym: N-(5-{[2-Amino-7-(2-hydroxy-1 ,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5- yl]carbonyl}pyridin-3-yl)-2-(5-chloropyridin-2-yl)acetamide; N-[5-[[2-Amino-7-(2-hydroxy-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl]-3-pyridinyl]-5-chloro-2-pyridineacetamide; PF 06273340; PF06273340

CAS Number: 1402438-74-7
Empirical Formula (Hill Notation): C23H22ClN7O3
Molecular Weight: 479.92
Linear Formula: C23H22ClN7O3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-PZ0254-5MG 5 mg
 $129.00
1/EA		 Add To Favorites
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assay ≥98% (HPLC)
color , white to yellow to brown
form powder
InChI 1S/C23H22ClN7O3/c1-23(2,12-32)31-11-18(17-10-28-22(25)30-21(17)31)20(34)13-5-16(9-26-7-13)29-19(33)6-15-4-3-14(24)8-27-15/h3-5,7-11,32H,6,12H2,1-2H3,(H,29,33)(H2,25,28,30)
InChI key BPIWZDNVMQQBQX-UHFFFAOYSA-N
Quality Level 100 
SMILES string CC(CO)(C)N1C2=NC(N)=NC=C2C(C(C3=CN=CC(NC(CC4=CC=C(Cl)C=N4)=O)=C3)=O)=C1
solubility DMSO: 20 mg/mL, clear
storage temp. room temp
Biochem/physiol Actions: PF-06273340 is a brain penetrant, orally available and potent tropomyosin-related kinase (Trk) inhibitor.
Biochem/physiol Actions: PF-06273340 is a brain penetrant, orally available and potent tropomyosin-related kinase (Trk) inhibitor. PF-06273340 is under development as a remedy acute and chronic pain.
Packaging: 5, 25 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P301 + P312 + P330
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 51111800

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