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Sulopenem

SIGMA/PZ0042 - ≥97% (HPLC)

Synonym: (5R,6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[[(1R,3S)-tetrahydro-1-oxido-3-thienyl]thio]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; CP-70429

CAS Number: 120788-07-0
Empirical Formula (Hill Notation): C12H15NO5S3
Molecular Weight: 349.45
Linear Formula: C12H15NO5S3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-PZ0042-5MG 5 mg
 $116.00
1/EA		 Add To Favorites
45-PZ0042-25MG 25 mg
 $467.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts PZ0042-5MG.

 

assay ≥97% (HPLC)
color white to beige
form powder
InChI 1S/C12H15NO5S3/c1-5(14)7-9(15)13-8(11(16)17)12(20-10(7)13)19-6-2-3-21(18)4-6/h5-7,10,14H,2-4H2,1H3,(H,16,17)/t5-,6?,7+,10-,21?/m1/s1
InChI key FLSUCZWOEMTFAQ-JNCILSLHSA-N
shipped in dry ice
SMILES string O=C(O)C1=C(S[C@@H]2C[S@+]([O-])CC2)S[C@@]3([H])N1C([C@]3([H])[C@H](O)C)=O
solubility DMSO: 2 mg/mL, clear
storage temp. −20°C
Biochem/physiol Actions: Orally available penem antibiotic to treat Gram-negative multi-drug resistant infections
Biochem/physiol Actions: Sulopenem is an orally available penem antibiotic designed to treat Gram-negative multi-drug resistant infections. It can be administered as an intravenous preparation, and it is also orally available.
Biochem/physiol Actions: Sulopenem, formerly CP-70,429, is stable to renal dehydropeptidase I and hydrolytic activity of AmpC β-lactamases and extended-spectrum β-lactamases (ESBLs) that convey resistance to third-generation cephalosporins. This action of sulopenem helps to act against urgent drug-resistant antimicrobial threats, including ESBL-producing Enterobacteriaceae. Sulopenem is effective than ciprofloxacin for treating urogenital upper urinary tract infection (uUTI) in adult women due to quinolone non-susceptible pathogens.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Purity ≥97% (HPLC)
Storage Temp. −20°C
UNSPSC 51111800

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