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Sulopenem

SIGMA/PZ0042 - ≥97% (HPLC)

Synonym: (5R,6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[[(1R,3S)-tetrahydro-1-oxido-3-thienyl]thio]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; CP-70429

CAS Number: 120788-07-0
Empirical Formula (Hill Notation): C12H15NO5S3
Molecular Weight: 349.45
Linear Formula: C12H15NO5S3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-PZ0042-5MG 5 mg
 $108.00
1/EA		 Add To Favorites
45-PZ0042-25MG 25 mg
 $436.00
1/EA		 Add To Favorites

 

assay ≥97% (HPLC)
color white to beige
form powder
InChI 1S/C12H15NO5S3/c1-5(14)7-9(15)13-8(11(16)17)12(20-10(7)13)19-6-2-3-21(18)4-6/h5-7,10,14H,2-4H2,1H3,(H,16,17)/t5-,6?,7+,10-,21?/m1/s1
InChI key FLSUCZWOEMTFAQ-JNCILSLHSA-N
shipped in dry ice
SMILES string O=C(O)C1=C(S[C@@H]2C[S@+]([O-])CC2)S[C@@]3([H])N1C([C@]3([H])[C@H](O)C)=O
solubility DMSO: 2 mg/mL, clear
storage temp. −20°C
Biochem/physiol Actions: Orally available penem antibiotic to treat Gram-negative multi-drug resistant infections
Biochem/physiol Actions: Sulopenem is an orally available penem antibiotic designed to treat Gram-negative multi-drug resistant infections. It can be administered as an intravenous preparation, and it is also orally available.
Biochem/physiol Actions: Sulopenem, formerly CP-70,429, is stable to renal dehydropeptidase I and hydrolytic activity of AmpC β-lactamases and extended-spectrum β-lactamases (ESBLs) that convey resistance to third-generation cephalosporins. This action of sulopenem helps to act against urgent drug-resistant antimicrobial threats, including ESBL-producing Enterobacteriaceae. Sulopenem is effective than ciprofloxacin for treating urogenital upper urinary tract infection (uUTI) in adult women due to quinolone non-susceptible pathogens.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Purity ≥97% (HPLC)
Storage Temp. −20°C
UNSPSC 51111800

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