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Monoclonal Anti-Protein Tyrosine Phosphatase PEST antibody produced in mouse

SIGMA/P9109 - clone AG25, purified immunoglobulin

Synonym: Anti-PTP PEST

MDL Number: MFCD02688691
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-P9109-.1MG 0.1 mg
$461.00
1/EA
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antibody form purified immunoglobulin
antibody product type primary antibodies
biological source mouse
clone AG25, monoclonal
conjugate unconjugated
isotype IgG1
mol wt antigen 88 kDa
Quality Level 200 
shipped in dry ice
species reactivity mouse, human, bovine, rat
storage temp. −20°C
target post-translational modification unmodified
technique(s) immunoprecipitation (IP): suitable
  western blot: suitable
UniProt accession no. Q05209 
Application: Anti-Protein Tyrosine Phosphatase PEST antibody is suitable for immunoblotting and immunoprecipitation.
Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description: Among the post-translational modifications, phosphorylation is a vital regulatory mechanism of key proteins involved in specific pathways. Reverse phosphorylation has become recognized as the key process of regulation of gene expression, cellular proliferation, differentiation in Eukaryotes. The protein phosphatases can be divided into two main groups: protein tyrosine phosphatases (PTPs) and protein serine/threonine phosphatases (PPs) which remove phosphate from proteins/peptides containing phosphotyrosine (pTyr) or phosphoserine/phosphothreonine (pSer/pThr), respectively. Several of the PTPs are known to control the function of growth factor receptors, many of which are tyrosine kinases encoded by oncogenes. PTP PEST is a cytosolic protein tyrosine phosphatase which is ubiquitously expressed in mammalian tissues. PTP PEST is subject to regulation via phosphorylation of Ser39 by both protein kinase C and protein kinase A
Monoclonal Anti-Protein Tyrosine Phosphatase PEST recognizes PTP PEST isoforms in all mammalian species (88 kDa).
Immunogen: full-length, recombinant PTP PEST.
Physical form: Solution in phosphate buffered saline containing 0.08% sodium azide.
Preparation Note: Purified from tissue culture supernatant using Protein G.
Hazard Codes Xn
Risk Statements 21/22
Safety Statements 36/37-60
RIDADR NONH for all modes of transport
WGK Germany nwg
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12352203

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