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Pentylenetetrazole

SIGMA/P6500

Synonym: α,β-Cyclopentamethylenetetrazole; 1,5-Pentamethylenetetrazole; 6,7,8,9-Tetrahydro-5H-tetrazolo[1,5-a]azepine; Metrazole

CAS Number: 54-95-5
Empirical Formula (Hill Notation): C6H10N4
Molecular Weight: 138.17
EC Number: 200-219-3
MDL Number: MFCD00005939
Linear Formula: C6H10N4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-P6500-25G 25 g
 $101.00
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45-P6500-50G 50 g
 $203.00
1/EA		 Add To Favorites
45-P6500-100G 100 g
 $375.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P6500-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P6500-50G

 

bp 194 °C/12 mmHg (lit.)
form powder
InChI 1S/C6H10N4/c1-2-4-6-7-8-9-10(6)5-3-1/h1-5H2
InChI key CWRVKFFCRWGWCS-UHFFFAOYSA-N
mp 59-61 °C (lit.)
Quality Level 100 
SMILES string C1CCc2nnnn2CC1
storage temp. −20°C
Application: Pentylenetetrazole has been used to induce seizures in zebra fish larvae, mice, and male wistar rats.
Biochem/physiol Actions: Pentylenetetrazole is a non-specific central nervous system (CNS) stimulant and convulsant. PTZ induces oxidative stress and increases cortical malondialdehyde content and affects hippocampus, resulting in seizures.
General description: Pentylenetetrazole (PTZ) is a tetrazole derivative and inhibitor of the γ aminobutyric acid (GABAA) and its receptor complex. PTZ is a convulsing agent used for inducing seizures. It can traverse the blood-brain barrier.
Packaging: 25, 50, 100 g in poly bottle
bp 194 °C/12 mmHg (lit.)
mp 59-61 °C (lit.)
Storage Temp. −20°C
UNSPSC 12352200

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