Sodium pyruvate
SIGMA/P4562 - powder, BioXtra, suitable for mouse embryo cell culture
Synonym: α-Ketopropionic acid sodium salt; 2-Oxopropanoic acid sodium salt; Pyruvic acid sodium salt
CAS Number: 113-24-6
Empirical Formula (Hill Notation): C3H3NaO3
Molecular Weight: 110.04
EC Number: 204-024-4
MDL Number: MFCD00002586
Linear Formula: CH3COCOONa
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P4562-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P4562-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P4562-5G
| assay | ≥99% |
| form | powder |
| InChI | 1S/C3H4O3.Na/c1-2(4)3(5)6 |
| InChI key | DAEPDZWVDSPTHF-UHFFFAOYSA |
| mp | >300 °C (lit.) |
| product line | BioXtra |
| Quality Level | 200  |
| SMILES string | [Na+].CC(=O)C([O-])=O |
| solubility | H2O: 100 mg/mL |
| storage temp. | 2-8°C |
| technique(s) | cell culture | embryo: suitable |
| Application: | Sodium pyruvate has been used: • as a supplement in Ca2+ + N-Tris(hydroxymethil)methy • as a supplement in TCM-199 hepes modification solution for cumulus-oocytes complexes (COC′s) culture • as a supplement in Dulbecco′s modified Eagle medium (DMEM) to culture mouse primary hepatocytes (MPHs) and also to intraperitoneally inject fasted mice for glucose production assessment |
| Biochem/physiol Actions: | Sodium pyruvate is mainly used as a constituent in culture broth and media. It exhibits anti-oxidation and anti-inflammatory properties. Hence sodium pyruvate is considered a possible therapy for allergic rhinitis. Sodium pyruvate might also be a new approach treating lactic acidosis. |
| Biochem/physiol Actions: | Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. Sodium pyruvate attenuates oxidative stress in vitro. The 100 mM solution should be diluted at 1:100 for most cell culture applications. This product has been qualified for use in mouse embryo cultures. |
| General description: | Pyruvate, the end-product of the glycolysis pathway, is the anion of pyruvic acid. |
| Packaging: | 5, 25, 100 g in poly bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H317 - H319 |
| Precautionary statements | P280 - P302 + P352 - P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% |
| mp | >300 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352207 |