Synonym: (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine salt; Perindopril tert-butylamine; S-9490
CAS Number: 107133-36-8
Empirical Formula (Hill Notation): C19H32N2O5 · C4H11N
Molecular Weight: 441.60
MDL Number: MFCD02313824
Linear Formula: C19H32N2O5 · C4H11N
Product Type: Chemical
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This image depicts P0094-50MG.
| assay |
≥98% (HPLC) |
| form |
powder |
| InChI |
1S/C19H32N2O5.C4H11N/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24;1-4(2,3)5/h12-16,20H,4-11H2,1-3H3,(H,23,24);5H2,1-3H3/t12-,13-,14-,15-,16-;/m0./s1 |
| InChI key |
IYNMDWMQHSMDDE-MHXJNQAMSA-N |
| originator |
Xoma |
| Quality Level |
100  |
| SMILES string |
CC(C)(C)N.CCC[C@H](N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O)C(=O)OCC |
| solubility |
H2O: 10 mg/mL, clear |
| storage temp. |
2-8°C |
| Biochem/physiol Actions: |
Perindopril erbumine is an angiotensin converting enzyme (ACE) inhibitor; antihypertensive. |
| Biochem/physiol Actions: |
Perindopril erbumine is an angiotensin converting enzyme (ACE) inhibitor; antihypertensive; becomes hydrolyzed in vivo to the active diacid metabolite; unlike the other ACE inhibitors, inhibits tumor growth in hepatocellular carcinoma cells due to suppression of VEGF levels; also suppresses angiotensin II production in vitro. Long-term therapy with this agent has a beneficial effect on the cerebral circulation by improving cerebral perfusion reserve in patients with previous minor stroke. |
| Features and Benefits: |
This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: |
This compound was developed by Xoma . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Packaging: |
50, 250 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |