Advanced Search



Ofloxacin

SIGMA/O8757 - fluoroquinolone antibiotic

Synonym: Dextrofloxacin

CAS Number: 82419-36-1
Empirical Formula (Hill Notation): C18H20FN3O4
Molecular Weight: 361.37
MDL Number: MFCD00226105
Linear Formula: C18H20FN3O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-O8757-1G 1 g
 $64.30
1/EA		 Add To Favorites
45-O8757-10G 10 g
 $322.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: O8757-1G

 

antibiotic activity spectrum Gram-negative bacteria
  Gram-positive bacteria
  mycobacteria
biological source synthetic
form powder
InChI 1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)
InChI key GSDSWSVVBLHKDQ-UHFFFAOYSA-N
mode of action DNA synthesis | interferes
  enzyme | inhibits
Quality Level 200 
SMILES string FC1=C(C3=[c]4[n](cc([c]([c]4=C1)=O)C(=O)O)C(CO3)C)N2CCN(CC2)C
solubility 1 M NaOH: soluble 50 mg/mL
storage temp. 2-8°C
Application: Ofloxacin is a synthetic fluoroquinolone with broad-spectrum antibacterial activity. It is a nalidixic acid analog. It is given to patients before undergoing retinal reattachment surgery.
Biochem/physiol Actions: Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, which haults DNA replication and cell division. Ofloxacin has been shown to convert LytA from the inactive E-form to the active C-form. It is a chiral molecule that inhibits pneumococcal cell wall-degrading virulence factors.
General description: Chemical structure: fluoroquinolone
Other Notes: Keep container tightly closed in a dry and well-ventilated place.
Packaging: 1, 10 g in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 51282956

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Tariffs & Effects on Pricing

Tariff note: As we navigate the current environment of tariff surcharges and mid-year manufacturer price increases, we want to keep you informed. While we have avoided making specific decisions thus far, we anticipate that we will be forced to implement a cost adjustment policy to offset the fees we have already been absorbing. We are committed to transparency and moderation in this process.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top