Synonym: 5-(Dimethylamino)-1-[4-(2-methylbenzamido)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepine hydrochloride; Mozavaptan hydrochloride; N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)phenyl]-2-methylbenzamide hydrochloride
CAS Number: 138470-70-9
Empirical Formula (Hill Notation): C27H29N3O2 · HCl
Molecular Weight: 464.00
MDL Number: MFCD11111965
Linear Formula: C27H29N3O2 · HCl
Product Type: Chemical
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This image depicts O1266-10MG.
| assay |
≥98% (HPLC) |
| color |
white to tan |
| form |
powder |
| InChI |
1S/C27H29N3O2.ClH/c1-19-9-4-5-10-22(19)26(31)28-21-16-14-20(15-17-21)27(32)30-18-8-13-24(29(2)3)23-11-6-7-12-25(23)30;/h4-7,9-12,14-17,24H,8,13,18H2,1-3H3,(H,28,31);1H |
| InChI key |
MOROBKPIULFQDC-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
Cl.CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c4ccccc14 |
| solubility |
DMSO: ≥15 mg/mL |
| storage temp. |
2-8°C |
| Biochem/physiol Actions: |
OPC 31260 is a vasopressin V2 selective antagonist. Arginine vasopressin (AVP) plays an important part in circulatory and water homeostasis. The V2 receptor subtype is important in water retention, cardiac remodeling in congestive heart failure (CHF), and renal hemodynamic alterations, and is considered a target for polysystic kidney disease. OPC-31260 has been shown to inhibit the development of polycystic kidney disease in several animal models. |
| Biochem/physiol Actions: |
Vasopressin V2 selective antagonist. |
| Disclaimer: |
air-sensitive, hygroscopic, store with desiccant |
| Packaging: |
10, 50 mg in glass bottle |
| Symbol |
GHS07 |
| Signal word |
Warning |
| Hazard statements |
H302 |
| Hazard Codes |
Xn |
| Risk Statements |
22 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
51111800 |