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Melanotan II acetate salt

SIGMA/M8693 - ≥95% (HPLC)

Synonym: Ac-[Nle4Asp5D-Phe7Lys10]α-MSH-(4-10)-NH2

CAS Number: 121062-08-6 (free base)
Empirical Formula (Hill Notation): C50H69N15O9 · xC2H4O2
Molecular Weight: 1024.18 (free base basis)
MDL Number: MFCD06795842
Linear Formula: C50H69N15O9 · xC2H4O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-M8693-1MG 1 mg
 $232.00
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assay ≥95% (HPLC)
color white
form lyophilized solid
InChI 1S/C50H69N15O9/c1-3-4-16-36(59-29(2)66)44(69)65-41-25-42(67)55-20-11-10-18-35(43(51)68)60-47(72)39(23-31-26-57-34-17-9-8-15-33(31)34)63-45(70)37(19-12-21-56-50(52)53)61-46(71)38(22-30-13-6-5-7-14-30)62-48(73)40(64-49(41)74)24-32-27-54-28-58-32/h5-9,13-15,17,26-28,35-41,57H,3-4,10-12,16,18-25H2,1-2H3,(H2,51,68)(H,54,58)(H,55,67)(H,59,66)(H,60,72)(H,61,71)(H,62,73)(H,63,70)(H,64,74)(H,65,69)(H4,52,53,56)/t35-,36-,37-,38+,39-,40-,41-/m0/s1
InChI key JDKLPDJLXHXHNV-MFVUMRCOSA-N
Quality Level 200 
shipped in dry ice
SMILES string [nH]1cncc1C[C@@H]2NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC2=O)Cc5ccccc5)CCCN=C(N)N)Cc3c4c([nH]c3)cccc4)C(=O)N)NC(=O)[C@@H](NC(=O)C)CCCC
solubility H2O: soluble 5 mg/mL
storage temp. −20°C
Amino Acid Sequence: Ac-Nle-Asp-His-Phe-Arg-Trp-Lys-NH2
Application: Melanotan II acetate salt has been used to study its inhibitory effects on feeding and energy expenditure in rats.
Biochem/physiol Actions: Melanotan II is a MC3-R/MC4-R melanocortin agonist.
General description: Melanotan II induces melanogenesis and thus increases skin pigmentation. It is an analog of α-melanocyte stimulating hormone.
Packaging: 1 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. −20°C
UNSPSC 51111800

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