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(±)-Methoxyverapamil hydrochloride

SIGMA/M5644 - ≥98%

Synonym: (±)-α-[3-[(2-(3,4-Dimethoxyphenyl)ethyl)methylamino]propyl]-3,4,5-trimethoxy-α-(1-methylethyl)benzeneacetonitrile hydrochloride; D 600; Gallopamil

CAS Number: 16662-47-8
Empirical Formula (Hill Notation): C28H40N2O5 · HCl
Molecular Weight: 521.09
MDL Number: MFCD00058000
Linear Formula: C28H40N2O5 · HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-M5644-50MG 50 mg
$160.00
1/EA
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45-M5644-250MG 250 mg
$628.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M5644-250MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M5644-50MG

 

assay ≥98%
InChI 1S/C28H40N2O5.ClH/c1-20(2)28(19-29,22-17-25(33-6)27(35-8)26(18-22)34-7)13-9-14-30(3)15-12-21-10-11-23(31-4)24(16-21)32-5;/h10-11,16-18,20H,9,12-15H2,1-8H3;1H
InChI key OKCRIUNHEQSXFD-UHFFFAOYSA-N
Quality Level 200 
SMILES string Cl[H].COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2cc(OC)c(OC)c(OC)c2)cc1OC
Application: (±)-Methoxyverapamil hydrochloride has been used:
• as calcium channel antagonist in Schistosoma mansoni parasite
• as calcium entry blocker in cultured macrophages
• in the inhibition of L-type voltage gated Ca2+-channels

Biochem/physiol Actions: Blocks L-type Ca2+ channels
General description: Methoxyverapamil is a calmodulin antagonist. It controls flagellar glycoprotein redistribution by modulating calcium signalling. Methoxyverapamil impacts the effect of intracellular calcium levels and affects the sperm capacitation function.
Packaging: 50, 250 mg in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98%
UNSPSC 12352200

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