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6α-Methylprednisolone 21-hemisuccinate sodium salt

SIGMA/M3781 - lyophilized powder

Synonym: 6α-Methylprednisolone sodium succinate; MPSL; 6α-Methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate

CAS Number: 2375-03-3
Empirical Formula (Hill Notation): C26H33NaO8
Molecular Weight: 496.53
EC Number: 219-156-8
MDL Number: MFCD00152612
Linear Formula: C26H33O8Na
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-M3781-25MG 25 mg
 $89.00
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45-M3781-250MG 250 mg
 $464.00
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45-M3781-1G 1 g
 $1470.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts M3781-1G.

 

assay ≥98.00% (TLC)
biological source synthetic
form lyophilized powder
InChI 1S/C26H34O8.Na/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24;/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31);/q;+1/p-1/t14-,16-,17-,19-,23+,24-,25-,26-;/m0./s1
InChI key FQISKWAFAHGMGT-SGJOWKDISA-M
Quality Level 100 
shipped in ambient
SMILES string [Na+].C[C@H]1CC2C3CC[C@](O)(C(=O)COC(=O)CCC([O-])=O)[C@@]3(C)C[C@H](O)C2[C@@]4(C)C=CC(=O)C=C14
solubility water: 50 mg/mL, clear, colorless to faintly yellow
sterility non-sterile
storage temp. room temp
technique(s) toxicology assay: suitable
Application: 6α-methylprednisolone 21-hemisuccinate sodium salt has been used to investigate glucocorticoid-induced osteonecrosis under hypoxic conditions in the MC3T3-E1 osteoblast cell line using a cell cytotoxicity assay, flow cytometry and western blotting.
Biochem/physiol Actions: Glucocorticoid with slightly longer half-life than that of prednisolone.
Physical form: Lyophilized containing ~5% phosphate buffer salts.
Symbol GHS08  GHS08
Signal word Danger
Hazard statements H351 - H360
Precautionary statements P201 - P308 + P313
Hazard Codes T
Risk Statements 61-40
Safety Statements 53-22-36/37/39-45
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98.00% (TLC)
Storage Temp. room temp
UNSPSC 51111800

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