MES

SIGMA/M3671 - low moisture content, ≥99% (titration)

Synonym: 2-(N-Morpholino)ethanesulfonic acid; 4-Morpholineethanesulfonic acid

CAS Number: 4432-31-9
Empirical Formula (Hill Notation): C₆H₁₃NO₄S
Molecular Weight: 195.24
EC Number: 224-632-3
MDL Number: MFCD00006181
Linear Formula: C₆H₁₃NO₄S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-M3671-50G	50 g	$127.00 1/EA	Add To Favorites
45-M3671-250G	250 g	$444.00 1/EA	Add To Favorites
45-M3671-1KG	1 kg	$1470.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: M3671-50G

Properties
Descriptions
Safety Info.
Basic Data

application(s)	clinical research diagnostic assay manufacturing life science and biopharma ( ) metabolomics ( )
assay	≥99% (titration)
color	white
density	1.23 g/cm³ at 20—25 °C
	1.27 g/cm³ at 20—25 °C
form	powder
impurities	≤1.0% water
InChI	1S/C6H13NO4S/c8-12(9,10)6-3-7-1-4-11-5-2-7/h1-6H2,(H,8,9,10)
InChI key	SXGZJKUKBWWHRA-UHFFFAOYSA-N
pH	2.5-4 (25 °C, 97.6 g/L)
pKa	6.1
Quality Level	400
SMILES string	OS(=O)(=O)CCN1CCOCC1
storage condition	dry at room temperature
useful pH range	5.5-6.7

Analysis Note:	Low moisture
Application:	It has been utilized as a buffer bicarbonate‐containing culture medium
Application:	MES has been used as a component of the elution buffer used to elute plasma from α2-macroglobulin affinity column. It has been used as an activation buffer during antibody conjugation to microparticles. MES has been used in the functionalization of microchannels during the creation of microfluidic-integrated surface plasmon resonance (SPR) platform for pathogen detection.
Features and Benefits:	• Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications • Effective Buffering from pH 5.5-6.7 (25 °C) with a pKa of 6.1 (25 °C) • Highly soluble in water • Minimal metal ion binding • Less toxic to cells than other buffers such as Tris and phosphate • Stable in a wide pH range • Low UV absorptivity and Minimal reactivity
General description:	MES Buffer, recognized as one of the "Good" buffers employed in biological and biochemical applications, plays a crucial role across various research domains. This zwitterionic and morpholinic buffer proves highly valuable due to its effective buffering capacity within the pH range of 5.5 to 6.7. Notably, MES Buffer does not engage in complex formation with the majority of metals commonly employed in environmental and biological studies. Its solubility in water is excellent, and it exhibits minimal lipid solubility, rendering it impermeable to membranes. This versatile buffer may find widespread application in maintaining a stable environment in solutions dedicated to cell culture media, protein-based buffer formulations, and electrophoresis running buffers. Its significance extends to the purification processes of antibodies, peptides, proteins, blood components, and growth factors. MES Buffer stands out as an optimal choice for capillary electrochromatography, offering low ionic mobility. Notably, it serves as a safer alternative to potentially toxic agents like cacodylate and non-zwitterionic buffers, including citrate and malate. MES Buffer also proves valuable for fine-tuning the pH of growth media, stabilizing enzymatic solutions, and serving as a component of PAGE running buffer in diverse experimental settings.
Other Notes:	For additional information on our range of Biochemicals , please complete this form .
Packaging:	1 kg in poly bottle
Packaging:	50, 250 g in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1

Purity	≥99% (titration)
Density	1.23 g/cm³ at 20—25 °C; 1.27 g/cm³ at 20—25 °C
UNSPSC	12161700

To Order From a Quote