Mucin from porcine stomach
SIGMA/M2378 - Type II
Synonym: MUC
CAS Number: 84082-64-4
EC Number: 282-010-7
MDL Number: MFCD00131629
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M2378-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M2378-500G
| biological source | Porcine stomach |
| composition | bound sialic acid, ≤1.2% |
| form | powder |
| Quality Level | 200  |
| solubility | 1 M NaOH: soluble 20 mg/mL |
| storage temp. | 2-8°C |
| technique(s) | cell culture | mammalian: suitable |
| type | Type II |
| UniProt accession no. | A0A5G2QSD1  |
| Application: | Mucin from porcine stomach has been used: • in the standard curve generation for quantifying mucin-2 generated during mucosal inflammation in mice • as a component of digestion fluid solutions in in vitro human digestion model • as a component of simulated saliva fluid |
| Application: | Mucin from porcine stomach was used in studies on the binding site of the galactose-specific agglutinin PA-IL from Pseudomonas aeruginosa. |
| Biochem/physiol Actions: | Mucin has wide pharmacological applications in drug delivery. Mucins play a protective role in inflammation. Deregulation in mucin synthesis contributes to tumorigenesis and chronic inflammation. |
| Biochem/physiol Actions: | Mucus forms the protective cover for all epithelial surfaces. The major structural component of mucus is gel-forming mucins. The mucus layer covering the intestinal epithelium has the MUC2 mucin as its central molecule. MUC2 is produced by goblet cells. |
| General description: | Mucin is majorly composed of carbohydrate units, crucial for structural architecture and conformation. The monomer of mucin is 640 kDa, with protein contributing to only 20% of the molecular weight. The carbohydrate component is attached to the threonine and serine side chains. Mucins are classified into secreted and transmembrane mucins. |
| General description: | Mucins or mucus glycoproteins are the main macromolecular components of mammalian mucus. It was also used in a study to evaluate the sputum smears concentrated by cyto-centrifugation for detection of acid-fast bacilli. |
| Packaging: | 100, 500 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352202 |