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Manganese(II) chloride solution

SIGMA/M1787 - BioReagent, storage temp.:room temp, Molecular Biology

Synonym: Manganese chlroide; Manganese(II) chloride; MnCl2

CAS Number: 7773-01-5
Empirical Formula (Hill Notation): Cl2Mn
Molecular Weight: 125.84
MDL Number: MFCD00011114
Linear Formula: MnCl2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-M1787-10X1ML 1 mL
 $49.10
10/EA		 Add To Favorites
45-M1787-100ML 100 mL
 $105.00
1/EA		 Add To Favorites

 

cation traces heavy metals (as Pb): ≤5 ppm
concentration 1.00 M±0.01 M
foreign activity DNase, Exonuclease; NICKase, Endonuclease; and protease, none detected
form liquid
grade Molecular Biology
InChI 1S/2ClH.Mn/h2*1H;/q;;+2/p-2
InChI key GLFNIEUTAYBVOC-UHFFFAOYSA-L
product line BioReagent
Quality Level 200 
SMILES string Cl[Mn]Cl
sterility 0.2 μm filtered
storage temp. room temp
Application: Manganese (II) chloride solution has been used:
• in manganese enhanced magnetic resonance imaging (MEMRI) to study neuronal disease and manganese toxicity
• in high ionic strength reaction mixture to determine RNA polymerase I and II activity
• in reverse transcription reaction mix as a source of Mn2+ ions
General description: Manganese (II) chloride (MnCl2) might play a key role in integrin activation. Manganese is indispensable for brain function and is an essential cofactor for several key enzymes like superoxide dismutase and enzymes involved in neurotransmitter synthesis. Manganese can modulate iron and calcium homeostasis. Manganese is also used in the magnetic resonance imaging to increase contrast while examining neuronal connections and brain cytoarchitecture. High levels of manganese is toxic to central nervous system and causes Parkinson′s like symptoms called as manganism. MnCl2 has been used in reverse transcription reaction mix to enhance the template-switching efficiency.
General description: MnCl2 solution is a source of manganese ions and has a variety of biological uses. In biochemistry, it can be used as a cofactor in restriction enzymes, such as BamH and EcoR V. In molecular biology, Mn2+ can be substituted for Mg2+ as a divalent metal ion to facilitate DNase I activity in presence of Ca2+.
Storage Temp. room temp
UNSPSC 12352302

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