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Muscimol

SIGMA/M1523 - powder

Synonym: 3-Hydroxy-5-aminomethyl-isoxazole; 5-Aminomethyl-3-hydroxy-isoxazole; 5-Aminomethyl-3-isoxazolol; Agarine; Pantherine

CAS Number: 2763-96-4
Empirical Formula (Hill Notation): C4H6N2O2
Molecular Weight: 114.10
EC Number: 220-430-4
MDL Number: MFCD00057894
Linear Formula: C4H6N2O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-M1523-5MG 5 mg
 $161.00
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45-M1523-10MG 10 mg
 $248.00
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45-M1523-25MG 25 mg
 $550.00
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color white to off-white
form powder
InChI 1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)
InChI key ZJQHPWUVQPJPQT-UHFFFAOYSA-N
Quality Level 200 
SMILES string NCC1=CC(=O)NO1
storage temp. 2-8°C
Application: Muscimol has been used:
• to reduce conditioned fear-expression in lateral amygdala (LA)
• to eliminate cortical cell response in ferrets
• to inactivate lateral magnocellular nucleus of the nidopallium (LMAN) in zebra finches
Biochem/physiol Actions: GABAA receptor agonist.
Features and Benefits: This compound is a featured product for Neuroscience research. Click here  to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound is featured on the GABAA Receptors  and GABAC Receptors  pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description: Muscimol is a psychoactive isoxazole component, which is found in Amanita muscaria and related mushrooms. It lowers cerebral glucose metabolism and increases the level of 5-hydroxytryptamine in brain. Muscimol has hallucinogenic effects. It is associated with distorted perceptions, nausea and vomiting.
Packaging: 5, 10, 25 mg in glass bottle
Storage Temp. 2-8°C
UNSPSC 12352200

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