IgA, Kappa from murine myeloma
SIGMA/M1421 - clone TEPC 15, purified immunoglobulin, buffered aqueous solution
Synonym: Mouse IgA-κ
MDL Number: MFCD00164795
Product Type: Chemical
Illustration of IgA, Kappa
| antibody form | purified immunoglobulin |
| assay | ≥90% (non-reduced, SDS-PAGE) |
| biological source | mouse |
| clone | TEPC 15, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 300  |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Application: | Anti-Mouse IgA, κ antibody was used as secondary antibody in ELISA and immunoflourescence. |
| Application: | IgA, Kappa from murine myeloma has been used in: • immunofluorescence assay • enzyme-linked immunosorbent assay (ELISA) • invasion assays • western blotting |
| Biochem/physiol Actions: | Antigen Specificity: phosphoryl choline |
| Biochem/physiol Actions: | Immunoglobulin G (IgG) helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces IgA, κ from murine myeloma is produced by TEPC 15 tumor line that is pristane-induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. The antibody is specific for κ chain of mouse IgA. The purified immunoglobulin preparation is non-reactive with anti-mouse IgM, IgG1, IgG2a, IgG2b, and IgG3. |
| General description: | The TEPC 15 tumor line that produces mouse IgA,k is pristane-induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. IgA molecules in the serum are mostly dimeric. IgA is found in saliva, tracheobronchial secretions, genitourinary secretions, milk and colostrum. |
| Physical form: | Solution in 0.02 M Tris buffered saline, pH 8.0, containing 0.02% sodium azide |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥90% (non-reduced, SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |