MOPS

SIGMA/M1254 - ≥99.5% (titration)

Synonym: 3-(N-Morpholino)propanesulfonic acid; 4-Morpholinepropanesulfonic acid

CAS Number: 1132-61-2
Empirical Formula (Hill Notation): C₇H₁₅NO₄S
Molecular Weight: 209.26
EC Number: 214-478-5
MDL Number: MFCD00006183
Linear Formula: C₇H₁₅NO₄S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-M1254-25G	25 g	$55.30 1/EA	Add To Favorites
45-M1254-100G	100 g	$122.00 1/EA	Add To Favorites
45-M1254-250G	250 g	$250.00 1/EA	Add To Favorites
45-M1254-1KG	1 kg	$741.00 1/EA	Add To Favorites
45-M1254-5KG	5 kg	$2650.00 1/EA	Add To Favorites
45-M1254-25KG	25 kg	$7880.00 1/EA	Add To Favorites
45-M1254-25KG-DP	25 kg	No Price
45-M1254-50KG	50 kg	$14360.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: M1254-100G

Properties
Descriptions
Safety Info.
Basic Data

λ	33 % in H₂O
application(s)	clinical research diagnostic assay manufacturing life science and biopharma
assay	≥99.5% (titration)
color	white
form	crystalline powder
InChI	1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)
InChI key	DVLFYONBTKHTER-UHFFFAOYSA-N
pH	2.5-4 (25 °C, 209 g/L)
pKa (25 °C)	7.2
Quality Level	200
SMILES string	OS(=O)(=O)CCCN1CCOCC1
solubility	water: 0.5 g/mL, clear, colorless
storage condition	dry at room temperature
storage temp.	room temp
suitability	suitable for HPLC
technique(s)	affinity chromatography: suitable
	electrophoresis: suitable
useful pH range	6.5-7.9

Application:	MOPS has been used as: • a cell culture additive component in lentiviral particle production • as a buffering agent in microbial growth medium and nuclei extraction buffer • as a component of the MMSE-A buffer for isolating heart mitochondria • as a component of the Synthetic Complete (SC) medium • as a buffer in fluorescence quenching of NADH
Features and Benefits:	• Ideal for Cell Biology and Biochemical research • Can be used as a Buffer component for Electrophoresis and Protein separation • Effective Buffering from pH 6.5-7.9 (25 °C) with a pKa of 7.2 (25 °C) • Highly soluble in water • Minimal metal ion binding
General description:	MOPS (3-(N-morpholino)propanesulfonic acid) also known as Propane Sultone buffer, is a versatile "Good′s buffer" extensively employed in biological research. It shares structural similarities with MES (2-(N-morpholino)ethanesulfonic acid), featuring a morpholine ring. In terms of physiological relevance, MOPS′ pKa of 7.2 closely aligns with physiological pH, making it suitable for studies requiring a near-neutral environment. Compared to MES with a pKa of 6.1, MOPS offers a more physiologically relevant buffering capacity. MOPS serves various functions in diverse research domains. As a buffering agent, it can be used to stabilize pH in cell culture media, promoting optimal cell growth and function. Additionally, it may find application in protein purification in chromatography, stabilizes protein solutions, and acts as a reliable running buffer in various electrophoretic techniques, enabling efficient separation and analysis of biomolecules. MOPS also efficiently lyses cells for subsequent protein or nucleic acid extraction and stabilizes enzymes in solution, ensuring their activity for research purposes. It further proves valuable in fine-tuning the pH of growth media for optimal cell growth. MOPS possesses additional advantages such as minimal interaction with metal ions especially with copper (Cu), nickel (Ni), manganese (Mn), zinc (Zn), cobalt (Co) ions, making it ideal for studies involving metal ions. It exhibits excellent water solubility, facilitating its use in various buffer formulations, and minimal lipid solubility, ensuring impermeability to membranes and minimizing interference with cellular processes. In summary, MOPS is a reliable buffer widely utilized across diverse biological disciplines, distinguished by its versatility, physiological relevance, minimal metal interaction, and ease of use, with its extensive applications in cell biology, protein studies, electrophoresis, and biochemical research.
Legal Information:	DRYPOUR is a registered trademark of Merck KGaA, Darmstadt, Germany
Legal Information:	Tyvek is a registered trademark of E. I. du Pont de Nemours and Company
Other Notes:	For additional information on our range of Biochemicals , please complete this form .
Packaging:	1 kg in poly bottle
Packaging:	25, 100, 250 g in poly bottle
Packaging:	5, 25, 50 kg in poly drum
Packaging:	The DRYPOUR^®packaging system for high-quality hygroscopic salts DRYPOUR^®packaging:• The current DRYPOUR^®packaging configuration is in a 50L nestable drum • 25KG-DP are the standard prepack offering • Smaller volumes can be put in the same drum for variable configurations The benefits of DRYPOUR^®:• Improves operational efficiency by reducing material preparation time and increasing operator safety • Minimizes caking of hygroscopic salts • Offers triple protection: against moisture inside and outside, and against contamination How does the DRYPOUR^®packaging system Improve your operational efficiency?• This state-of-the-art design packaging system minimizes caking, thus significantly reducing the time needed for material preparation • PE drum with our new tamper-evident seal, a polyethylene liner with integrated desiccant bags and a breathable interior Tyvek^®liner • Desiccant bags are firmly integrated into the polyethylene liner • Triple protection delivers two invaluable results: Dramatically reduced caking No contamination risk from the desiccant

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	230.0 °F - closed cup
Flash Point(C)	110 °C - closed cup

Purity	≥99.5% (titration)
Storage Temp.	room temp
UNSPSC	12161700

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