Anti-Muscarinic Acetylcholine Receptor (M3) antibody produced in rabbit
SIGMA/M0194 - affinity isolated antibody, lyophilized powder
Synonym: Muscarinic Acetylcholine Receptor M3 Antibody; Muscarinic Acetylcholine Receptor M3 Antibody - Anti-Muscarinic Acetylcholine Receptor (M3) antibody produced in rabbit
MDL Number: MFCD06798471
Product Type: Chemical
Immunoblotting Anti-M3 Muscarinic Receptor: Cat. No. M0194: Western blot analysis of Rat brain lysate. Lanes 1. Anti-M3 Muscarinic Receptor antibody, (1:200). 2. Anti-M3 Muscarinic Receptor antibody, preincubated with the control peptide antigen.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | lyophilized powder |
| Quality Level | 200  |
| shipped in | dry ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified, unmodified |
| technique(s) | western blot: 1:200 using rat brain lysate |
| UniProt accession no. | P20309  |
| Application: | Anti-Muscarinic Acetylcholine Receptor (M3) antibody produced in rabbit has been used in immunohistochemistry and western blotting. |
| Application: | Rabbit polyclonal anti-Muscarinic Acetylcholine Receptor (M3) antibody is used to tag muscarinic acetylcholine receptor (M3) for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of muscarinic acetylcholine receptor (M3) in information processing and plastic changes in CNS function. |
| Biochem/physiol Actions: | Muscarinic receptor 3 (M3R) is involved in the contraction of the detrusor muscle. It is also involved in the secretion of saliva and bladder contraction. It participates in several pathological processes of lung disease, such as chronic obstructive pulmonary disease (COPD). Mutations in the CHRM3 gene is associated with congenital bladder malformations related to prune-belly-like syndrome (PBS). |
| Biochem/physiol Actions: | Rabbit polyclonal anti-Muscarinic Acetylcholine Receptor (M3) antibody recognizes rat, human, mouse Muscarinic Acetylcholine Receptor (M3). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Cholinergic receptor muscarinic 3 (CHRM3) gene is located on the human chromosome at 1q43 and encodes for the M3 subtype of muscarinic acetylcholine |
| Immunogen: | synthetic peptide corresponding to amino acid residues 461-479 of the third intracellular loop of rat muscarinic acetylcholine receptor M3. This sequence is identical in human, mouse, pig, and bovine. |
| Physical form: | Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide. |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H302 + H332 - H311 - H412 |
| Precautionary statements | P273 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 |
| Hazard Codes | T |
| Risk Statements | 24/25-52/53 |
| Safety Statements | 36/37-45-61 |
| RIDADR | UN 3288 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |