N-Lauroylsarcosine sodium salt
SIGMA/L9150 - detergent for use in cell lysis
Synonym: Sodium lauroyl sarcosinate; N-Dodecanoyl-N-methylglycine sodium salt; Sarkosyl NL
CAS Number: 137-16-6
Empirical Formula (Hill Notation): C15H28NNaO3
Molecular Weight: 293.38
EC Number: 205-281-5
MDL Number: MFCD00042728
Linear Formula: CH3(CH2)10CON(CH3)CH2COONa
Product Type: Chemical
| aggregation number | 2 |
| assay | ≥94% |
| CMC | 14.6 mM (20-25°C) |
| description | anionic |
| foreign activity | DNase, RNase, none detected |
| form | powder |
| grade | Molecular Biology |
| InChI | 1S/C15H29NO3.Na/c1-3-4-5- |
| InChI key | KSAVQLQVUXSOCR-UHFFFAOYSA |
| mol wt | micellar avg mol wt 600 |
| product line | BioReagent |
| Quality Level | 200 ![]() |
| SMILES string | [Na+].CCCCCCCCCCCC(=O)N(C |
| solubility | H2O: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow |
| storage temp. | room temp |
| technique(s) | protein purification: suitable |
| protein quantification: suitable |
| Application: | Suitable for • solubilization and separation of membrane proteins • lysis of cells during the isolation of RNA • inhibition of hexokinase |
| Features and Benefits: | • Suitable for Molecular Biology, Biochemical and Cell Biology research • Can be used for Protein Purification and Quantification • High purity product for research applications |
| General description: | Sodium lauroyl sarcosinate, the sodium salt of an acyl derivative of sarcosine—a natural amino acid occurring in muscles and body tissues—stands out as a valuable component in molecular biology, biochemical, and cell biology research. Derived from a natural fatty acid and the amino acid derivative sarcosine, N-Lauroylsarcosine is a biodegradable anionic surfactant usually synthesized through acylation and neutralization reactions involving lauric acid and sodium sarcosine. This amino acid-type anionic surfactant, also recognized as a fatty acid amide and detergent, exhibits protein denaturant potency and has been integrated into lysing solutions, such as the cornet assay. Its application extends to lysing protoplasts for chromosomal DNA isolation from Streptococcus mutans. Notably, Lauroylsarcosine Sodium Salt, characterized by its ionic detergent properties, is commonly employed for purifying membrane proteins. Additionally, Sodium Lauroyl Sarcosine also plays a crucial role in concentrated salt solutions, facilitating cell lysis in RNA purification protocols and membrane solubilization. Whether it′s breaking down cell structures or facilitating membrane protein purification, this mild surfactant proves valuable in various applications within the realms of biology and biochemistry. |
| Other Notes: | Anionic surfactant. |
| Other Notes: | For additional information on our range of Biochemicals , please complete this form . |
| Packaging: | 50, 100, 250 g in poly bottle |
| Symbol | ![]() GHS05,GHS06 |
| Signal word | Danger |
| Hazard statements | H315 - H318 - H330 |
| Precautionary statements | P260 - P264 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | T |
| Risk Statements | 23-38-41 |
| Safety Statements | 22-26-37/39-38-45 |
| RIDADR | UN 2811 6.1 / PGII |
| WGK Germany | WGK 1 |
| Flash Point(F) | 512.6 °F - closed cup |
| Flash Point(C) | 267 °C - closed cup |
| Purity | ≥94% |
| Storage Temp. | room temp |
| UNSPSC | 12161902 |



