Linoleic Acid-Albumin from bovine serum albumin
SIGMA/L8384 - γ-irradiated, lyophilized powder, BioReagent, suitable for cell culture
Product Type: Chemical
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| biological source | bovine plasma |
| concentration | >0.5% (linolenic acid) |
| description | Contains 1.1-2.3 moles linoleic acid per mole BSA |
| form | lyophilized powder |
| impurities | ≤50 EU/mg endotoxin |
| product line | BioReagent |
| Quality Level | 200  |
| solubility | water: 10 mg/mL, clear to hazy, colorless to light yellow |
| sterility | γ-irradiated |
| storage temp. | 2-8°C |
| technique(s) | cell culture | mammalian: suitable |
| Application: | Linoleic Acid-Albumin from bovine serum albumin has been used: in cell culture and to study its effects on the human colonic adenocarcinoma cell line. It has also been used in the in vitro culture (IVC) of cow embryos/zygotes. The binding of linoleic acid to BSA improves its stability and solubility in culture media. |
| Biochem/physiol Actions: | Linoleic acid plays a role in maintaining the transdermal water barrier in epidermis. Serum albumin constitutes about 52-62% of the total water-soluble fraction proteins in the blood plasma. |
| General description: | Linoleic acid is an essential and highly consumed polyunsaturated fatty acid (PUFA). Albumin is a globular protein. Bovine serum albumin (BSA) is composed of a single polypeptide chain and cross-linked cysteine disulfide bridges. BSA is heart-shaped and is made up of three homologous domains I-III and each domain has two subdomains A and B. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352202 |