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Leu-Leu methyl ester hydrobromide

SIGMA/L7393 - ≥97% (TLC)

Synonym: LLME, HBr; Leu-Leu-Ome, HBr

CAS Number: 16689-14-8
Empirical Formula (Hill Notation): C13H26N2O3 · HBr
Molecular Weight: 339.27
MDL Number: MFCD00216855
Linear Formula: C13H26N2O3 · HBr
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-L7393-500MG 500 mg
$367.00
1/EA
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assay ≥97% (TLC)
color white
form powder
InChI 1S/C13H26N2O3.BrH/c1-8(2)6-10(14)12(16)15-11(7-9(3)4)13(17)18-5;/h8-11H,6-7,14H2,1-5H3,(H,15,16);1H
InChI key QIPBCIHWFATZOF-UHFFFAOYSA-N
Quality Level 200 
SMILES string Br.COC(=O)C(CC(C)C)NC(=O)C(N)CC(C)C
storage temp. −20°C
Application:

  • VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.: The article discusses the maintenance of lysosomal function and transcription factor activity in muscle cells, which may be influenced by small molecular agents like Leu-Leu methyl ester hydrobromide that affect cellular processes (Arhzaouy et al., 2019 ).

Biochem/physiol Actions: Leu-Leu methyl ester (LLME, Leu-Leu-OMe) may be used to induce protease-dependent cell death (apoptosis) in immune cells such as mast cells, phagocytes, monocytes/macrophages and natural killer cells.
Biochem/physiol Actions: Peptide toxic to natural killer T cells.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥97% (TLC)
Storage Temp. −20°C
UNSPSC 12352209

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