Lumefantrine

SIGMA/L5420

Synonym: (9Z)-2,7-Dichloro-9-[(4-chlorophenyl)methylene]-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol; Benflumetol; CPG-56695

CAS Number: 82186-77-4
Empirical Formula (Hill Notation): C₃₀H₃₂Cl₃NO
Molecular Weight: 528.94
MDL Number: MFCD05662268
Linear Formula: C₃₀H₃₂Cl₃NO
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-L5420-5MG	5 mg	$129.00 1/EA	Add To Favorites
45-L5420-25MG	25 mg	$549.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	yellow
form	powder
InChI	1S/C30H32Cl3NO/c1-3-5-13-34(14-6-4-2)19-29(35)28-18-23(33)17-27-25(15-20-7-9-21(31)10-8-20)26-16-22(32)11-12-24(26)30(27)28/h7-12,15-18,29,35H,3-6,13-14,19H2,1-2H3/b25-15-
InChI key	DYLGFOYVTXJFJP-MYYYXRDXSA-N
originator	Novartis
Quality Level	100
SMILES string	CCCCN(CCCC)CC(O)c1cc(Cl)cc2C(=C/c3ccc(Cl)cc3)c4cc(Cl)ccc4-c12
solubility	DMSO: 2 mg/mL, clear (warmed)
storage temp.	room temp

Application:	Lumefantrine has been used: to study its effect on ex-vivo Plasmodium falciparum sensitivity using the tritiated hypoxanthine-based assay as a standard in the quantification of combined tablet formulation using HPTLC as a drug molecule in in vitro growth inhibition assay for in vitro B. caballi growth inhibition studies
Biochem/physiol Actions:	Lumefantrine is is an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria.
Features and Benefits:	This compound was developed by Novartis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description:	Lumefantrine, also known as benflumetol is an aryl-amino alcohol. It is a member of the group of arylamine alcohols like quinine, mefloquine and halofantrine.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	room temp
UNSPSC	12352200

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