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Latrunculin B from Latruncula magnifica

SIGMA/L5288 - ≥80% (HPLC), solid

Synonym: LAT-B

CAS Number: 76343-94-7
Empirical Formula (Hill Notation): C20H29NSO5
Molecular Weight: 395.51
MDL Number: MFCD00270879
Linear Formula: C20H29NSO5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-L5288-1MG 1 mg
 $331.00
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assay ≥80% (HPLC)
form solid
InChI 1S/C20H29NO5S/c1-13-5-3-4-6-14(2)9-18(22)25-16-10-15(8-7-13)26-20(24,11-16)17-12-27-19(23)21-17/h3,5,9,13,15-17,24H,4,6-8,10-12H2,1-2H3,(H,21,23)/b5-3-,14-9-/t13-,15-,16-,17+,20-/m1/s1
InChI key NSHPHXHGRHSMIK-JRIKCGFMSA-N
mol wt 395.5
Quality Level 200 
SMILES string C[C@H]1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]3CSC(=O)N3)OC(=O)C=C(C)CCC=C1
solubility ethanol: soluble
storage temp. −20°C
Application: Latrunculin B from Latruncula magnifica has been used for actin depolymerisation in various experiments. It has also been used as a component in bone marrow-derived dendritic cell (BMDC) complete medium, to study the formation of tubules from phagosomes in dendritic cells.
Biochem/physiol Actions: Latrunculin B inhibits actin polymerization in vitro. Latrunculin B disrupts microfilament-mediated processes.
General description: Latrunculin B is a macrocyclic toxin, which is produced by Latruncula magnifica.
Other Notes: 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research 
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥80% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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