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Lycorine hydrochloride

SIGMA/L5139 - ≥98% (TLC), powder

Synonym: Licorin hydrochloride; Lychorine chloride; Lycorine HCl

CAS Number: 2188-68-3
Empirical Formula (Hill Notation): C16H17NO4 · HCl
Molecular Weight: 323.77
MDL Number: MFCD00243111
Linear Formula: C16H17NO4 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-L5139-20MG 20 mg
 $371.00
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assay ≥98% (TLC)
form powder
InChI 1S/C16H17NO4.ClH/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19;/h3-5,11,14-16,18-19H,1-2,6-7H2;1H/t11-,14-,15+,16+;/m0./s1
InChI key VUVNTYCHKZBOMV-NVJKKXITSA-N
mp 210-212  °C
Quality Level 100 
SMILES string Cl.O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4[C@H]([C@@H]1O)[C@@H]23
solubility ethanol: 10 mg/mL, clear, colorless to very faintly yellow
storage temp. 2-8°C
Biochem/physiol Actions: A selective inhibitor of peptidyl transferase center (PTC).
Biochem/physiol Actions: A selective inhibitor of peptidyl transferase center (PTC). In HL-60 (leukemia) cells, lycorine arrests the cell cycle at G2/M and induces apoptosis by a caspase-mediated pathway.
Disclaimer: Protect from light.
Symbol GHS06  GHS06
Signal word Danger
Hazard statements H301
Precautionary statements P301 + P310
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR UN 2811 6.1 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (TLC)
mp 210-212  °C
Storage Temp. 2-8°C
UNSPSC 12352202

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