Sodium dodecyl sulfate
SIGMA/L3771 - BioReagent, suitable for electrophoresis, Molecular Biology, ≥98.5% (GC)
Synonym: Dodecyl sodium sulfate; Dodecyl sulfate sodium salt; Lauryl sulfate sodium salt; SDS; Sodium lauryl sulfate
CAS Number: 151-21-3
Empirical Formula (Hill Notation): C12H25NaO4S
Molecular Weight: 288.38
EC Number: 205-788-1
MDL Number: MFCD00036175
Linear Formula: CH3(CH2)11OSO3Na
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: L3771-25G
This image depicts SKU: L3771-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: L3771-100G
This image depicts SKU: L3771-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: L3771-500G
This image depicts SKU: L3771-500G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: L3771-1KG
This image depicts SKU: L3771-1KG
| absorption | ≤0.1 at 260 at 3% |
| ≤0.1 at 280 at 3% | |
| aggregation number | 62 |
| anion traces | chloride (Cl-): ≤500 ppm |
| phosphate (PO43-): ≤10 ppm | |
| assay | ≥98.5% (GC) |
| biological source | synthetic |
| cation traces | heavy metals (as Pb): ≤10 ppm |
| CMC | 7-10 mM (20-25°C) |
| density | 1.03 g/cm3 at 20 °C (68 °F) |
| description | anionic |
| foreign activity | DNase, RNase, none detected |
| form | powder |
| grade | Molecular Biology |
| HLB | 40 |
| impurities | ≤2.0% water (Karl Fischer) |
| InChI | 1S/C12H26O4S.Na/c1-2-3-4- |
| InChI key | DBMJMQXJHONAFJ-UHFFFAOYSA |
| mol wt | micellar 18,000 |
| mp | 204-207 °C (lit.) |
| product line | BioReagent |
| Quality Level | 200  |
| SMILES string | [Na+].CCCCCCCCCCCCOS([O-] |
| solubility | water: soluble |
| storage temp. | room temp |
| suitability | suitable for electrophoresis |
| technique(s) | electrophoresis: suitable |
| transition temp | cloud point >100 °C |
| Analysis Note: | Tested for use in denatured polyacrylamide gel electrophoresis. |
| Application: | Anionic detergent |
| Application: | Sodium dodecyl sulfate has been used: • in chromatin immunoprecipitation • in SDS-polyacrylamide gel electrophoresis (SDS-PAGE) • as a component of radioimmunoprecipitation assay buffer for immunoblotting |
| Application: | Used to solubilize and denature proteins for denaturing-PAGE. Most proteins bind SDS in a ratio of 1.4 g SDS per gram of protein. The charges intrinsic to the protein become insignificant compared to the overall negative charge provided by the bound SDS. The charge to mass ratio is essentially the same for each protein and will migrate in the gel based only on their size. |
| Features and Benefits: | • Highly versatile surfactant for your molecular biology and biochemical research • Suitable for electrophoresis applications • Tested to confirm low levels of heavy metal contamination,ensuring suitability for various applications. |
| General description: | Sodium dodecyl sulfate (SDS), also known as sodium lauryl sulfate, is an anionic surfactant widely used in various scientific applications, particularly in molecular biology, biochemical, and cell biology research. Its effectiveness stems from its amphiphilic nature, allowing it to interact with both hydrophobic and hydrophilic molecules. SDS is a versatile detergent that excels in solubilizing and denaturing proteins, making it an essential tool in protein extraction and purification procedures. By disrupting protein structures, SDS facilitates the separation of proteins based on their molecular weight during SDS-PAGE electrophoresis. Beyond protein analysis, SDS also finds applications in the electrophoretic separation of lipids, enabling the study and characterization of these important cellular components. Additionally, SDS is employed in various hybridization and molecular biology techniques, demonstrating its versatility across a range of research areas. SDS′s effectiveness in both ionic and anionic conditions further expands its utility, allowing it to adapt to diverse experimental setups and requirements. Its ability to unravel proteins by binding to peptide chains and imparting a negative charge effectively eliminates protein shape as a factor for gel separation, ensuring accurate protein size determination. |
| Other Notes: | 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research  |
| Other Notes: | For additional information on our range of Biochemicals , please complete this form . |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 25, 100, 500 g in poly bottle |
| Symbol |    GHS02,GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H228 - H302 + H332 - H315 - H318 - H335 - H412 |
| Precautionary statements | P210 - P273 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338 |
| Hazard Codes | F,Xn |
| Risk Statements | 11-21/22-37/38-41 |
| Safety Statements | 26-36/37-39 |
| RIDADR | UN1325 - class 4.1 - PG 3 - Flammable solids, organic, n.o.s., H |
| WGK Germany | WGK 2 |
| Flash Point(F) | 338.0 °F |
| Flash Point(C) | 170 °C |
| Purity | ≥98.5% (GC) |
| mp | 204-207 °C (lit.) |
| Density | 1.03 g/cm3 at 20 °C (68 °F) |
| Storage Temp. | room temp |
| UNSPSC | 12161902 |