LY-354740 hydrate
SIGMA/L1045 - ≥98% (HPLC)
Synonym: (1S,2S,5R,6S)
Empirical Formula (Hill Notation): C8H11NO4 · xH2O
Molecular Weight: 185.18 (anhydrous basis)
Linear Formula: C8H11NO4 · xH2O
Product Type: Chemical
| assay | ≥98% (HPLC) |
| form | solid |
| originator | Eli Lilly |
| Quality Level | 100 ![]() |
| solubility | deionized water: 8 mg/mL |
| storage temp. | room temp |
| Application: | LY-354740 hydrate has been used as a metabotropic glutamate receptor group II/III agonist to study its behavioral effectsof electric shock on Gammarus fossarum. |
| Biochem/physiol Actions: | LY-354740 is a highly selective and potent agonist of group II mGlu (metabotropic glutamate) receptors. |
| Biochem/physiol Actions: | LY-354740 is a highly selective and potent agonist of group II mGlu (metabotropic glutamate) receptors. It displays antianxiety and antiaddictive activity in vivo. It?s orally and systemically active. It is anxiolytic and inhibits symptoms of morphine withdrawal in morphine-dependent mice. |
| Features and Benefits: | This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Features and Benefits: | This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by Eli Lilly . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Packaging: | 5, 25 mg in glass bottle |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 22-24/25-36/37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | room temp |
| UNSPSC | 12352209 |


