Dichloromethane
SIGMA/L090000
Synonym: Methylene chloride
CAS Number: 75-09-2
Empirical Formula (Hill Notation): CH2Cl2
Molecular Weight: 84.93
EC Number: 200-838-9
MDL Number: MFCD00000881
Linear Formula: CH2Cl2
Product Type: Chemical
| autoignition temp. | 1223 °F |
| bp | 39.8-40 °C (lit.) |
| color | clear |
| contains | amylene as stabilizer |
| density | 1.325 g/mL at 25 °C (lit.) |
| expl. lim. | 22 % |
| form | liquid |
| impurities | ≤50 ppm water content (Karl Fischer) |
| InChI | 1S/CH2Cl2/c2-1-3/h1H2 |
| InChI key | YMWUJEATGCHHMB-UHFFFAOYSA |
| mp | −95 °C (lit.) |
| product line | Proligo Reagents |
| Quality Level | 200  |
| refractive index | n |
| n |
|
| SMILES string | ClCCl |
| storage condition | dry at room temperature |
| technique(s) | DNA synthesis: suitable |
| type | for DNA synthesis |
| vapor density | 2.9 (vs air) |
| vapor pressure | 24.45 psi ( 55 °C) |
| 6.83 psi ( 20 °C) |
| Application: | Dichloromethane may be used as a solvent for the preparation of stock solutions of carotenoids. It may be employed as a solvent in the synthesis of polylactide-based (PLA) thin films. IT is also suitable as a solvent for the oxidation of primary and secondary alcohols using dipyridine-chromium(VI) oxide. |
| General description: | In the solid-phase synthesis of oligonucleotides, liquid reagents are used in each step of the synthesis cycle. Overall synthesis performance, and therefore total product yield and purity of the crude oligonucleotide, is highly dependent on the chemical purity of the monomers and the supporting liquid reagents and other solvents like ethylacetate, dichloromethane, and dimethylformadine .Dichloromethane is an ordinary organic solvent frequently utilized in peptide synthesis. Under normal circumstances, DCM maintains highly stable and will not cause significant side reactions in peptide synthesis. It is a chlorinated organic solvent that is susceptible to degradation with time. This can be suppressed by adding amylene as a stabilizer.Dichloromethan |
| Symbol |   GHS07,GHS08 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H336 - H351 |
| Precautionary statements | P201 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-40-67 |
| Safety Statements | 23-24/25-36/37 |
| RIDADR | UN 1593 6.1 / PGIII |
| Flash Point(F) | does not flash |
| Flash Point(C) | does not flash |
| bp | 39.8-40 °C (lit.) |
| mp | −95 °C (lit.) |
| Density | 1.325 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352101 |