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PKF118-310

SIGMA/K4394 - ≥98% (HPLC)

Synonym: 1,6-Dimethyl-pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione; Toxoflavin; Xanthothricin

CAS Number: 84-82-2
Empirical Formula (Hill Notation): C7H7N5O2
Molecular Weight: 193.16
MDL Number: MFCD00459812
Linear Formula: C7H7N5O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-K4394-5MG 5 mg
 $178.00
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45-K4394-25MG 25 mg
 $712.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts K4394-25MG.

 

assay ≥98% (HPLC)
color white to light brown
form powder
InChI 1S/C7H7N5O2/c1-11-6(13)4-5(10-7(11)14)12(2)9-3-8-4/h3H,1-2H3
InChI key SLGRAIAQIAUZAQ-UHFFFAOYSA-N
Quality Level 100 
SMILES string CN1N=CN=C(C1=N2)C(N(C)C2=O)=O
solubility H2O: 10 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: PKF118-310 is a Tcf4/b-catenin antagonist.
Biochem/physiol Actions: PKF118-310 is an antagonist of the Tcf4/b-catenin signaling. The compound disrupts the Tcf4/b-catenin complex and inhibits expression of Tcf4 responsive genes. PKF118-310 inhibits expression of survivin and induces apoptosis in HCC, colon tumor and lymphocytic leukemia cell lines.
Packaging: 5, 25 mg in glass bottle
Symbol GHS06  GHS06
Signal word Danger
Hazard statements H300
Precautionary statements P264 - P270 - P301 + P310 - P405 - P501
Hazard Codes T
Risk Statements 28
Safety Statements 45-46
RIDADR UN 2811 6.1 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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