Advanced Search



K 858

SIGMA/K3644 - ≥98% (HPLC)

Synonym: K858; N-(4-Acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadia zol-2-yl)acetamide

CAS Number: 72926-24-0
Empirical Formula (Hill Notation): C13H15N3O2S
Molecular Weight: 277.34
MDL Number: MFCD00181155
Linear Formula: C13H15N3O2S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-K3644-25MG 25 mg
 $272.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to off-white
form powder
InChI 1S/C13H15N3O2S/c1-9(17)14-12-15-16(10(2)18)13(3,19-12)11-7-5-4-6-8-11/h4-8H,1-3H3,(H,14,15,17)
InChI key JEFVYQYZCAVNTP-UHFFFAOYSA-N
Quality Level 100 
SMILES string CC(=O)NC1=NN(C(C)=O)C(C)(S1)c2ccccc2
solubility DMSO: ≥20 mg/mL
storage temp. 2-8°C
Biochem/physiol Actions: A thiadiazoline derivative reported as a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor.
Biochem/physiol Actions: Eg5 is a key protein involved in the formation of bipolar spindles. K858 is a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor. The compound induces mitotic arrest, caspase-3 activation and cell growth inhibition in HCT116 cells.
Packaging: 5, 25 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352202

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Tariffs & Effects on Pricing

Tariff note: As we navigate the current environment of tariff surcharges and mid-year manufacturer price increases, we want to keep you informed. While we have avoided making specific decisions thus far, we anticipate that we will be forced to implement a cost adjustment policy to offset the fees we have already been absorbing. We are committed to transparency and moderation in this process.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top